Author

R. Hua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. A. Minassian· 1 shared B. Wang· 1 shared C. He· 1 shared C. Liang· 1 shared D. Zhou· 1 shared F. M. Acosta· 1 shared G. L. Beilhartz· 1 shared G. Xu· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. A. Minassian

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification of Circular Dorsal Ruffles as Signal Platforms for the AKT pathways in Glomerular Podocytes

S. Yoshida, R. Hua, M. Torres, X. Sun, J. Wei, L. Wang, K. Inoki

The paper identifies circular dorsal ruffles as signal platforms for the AKT-mTORC1 pathway in glomerular podocytes, linking them to kidney function and potential therapeutic targets.

Journal of Cellular Physiology · Mar 16, 2023Peer-reviewedCell Biology

Connexin 43 Hemichannels Regulate Mitochondrial ATP Generation, Mobilization, and Mitochondrial Homeostasis against Oxidative Stress

J. Zhang, M. A. Riquelme, R. Hua, F. M. Acosta, S. Gu, J. X. Jiang

This study shows that mitochondrial Cx43 hemichannels regulate mitochondrial ATP production and protect osteocytes from oxidative stress by facilitating ion and ATP transfer and interacting with ATP synthase.

bioRxiv · Aug 5, 2022Cell Biology

Underlying beneficial effects of Rhubarb on constipation-induced inflammation, disorder of gut microbiome and metabolism

H. Gao, C. He, R. Hua, C. Liang, B. Wang, Y. Du, Y. Guo, L. Gao, L. Zhang, H. Shang, J. Xu

This study investigates rhubarb's effects on constipation-induced inflammation, gut microbiome, and metabolism in mice, showing improvements in cytokine balance, microbial diversity, and fatty acid metabolism.

bioRxiv · Jun 24, 2022 · PreprintPharmacology & Toxicology

Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat

Z. Zheng, R. Hua, G. Xu, H. Yang, P. Shi

This study identifies gene losses in subterranean rodents, showing their potential role in hypoxia tolerance and other adaptations.

bioRxiv · May 28, 2021Evolutionary Biology

Exploiting toxin internalization receptors to enhance delivery of proteins to lysosomes for enzyme replacement therapy

S. Sugiman-Marangos, G. L. Beilhartz, X. Zhao, D. Zhou, R. Hua, P. K. Kim, J. M. Rini, B. A. Minassian, R. A. Melnyk

This study creates a chimera of diphtheria toxin and TPP1 to enhance lysosomal enzyme delivery, showing improved uptake and efficacy in a mouse model.

bioRxiv · Jan 22, 2020Pharmacology & Toxicology