Author

S. Moriyama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Assay:metabolomics· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Y. Takahashi· 4 shared T. Suzuki· 3 shared P. Wiriyasermkul· 2 shared S. Fukushi· 2 shared S. Nagamori· 2 shared A. Matsuda· 1 shared A. Nishiyama· 1 shared C. Makino-Okamura· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

Y. Takahashi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Fc-modified SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.

M. Takeshita, H. Fukuyama, K. Kamada, T. Matsumoto, C. Makino-Okamura, T. Uchikubo-Kamo, Y. Tomabechi, K. Hanada, S. Moriyama, Y. Takahashi, H. Ishigaki, M. Nakayama, C. T. Nguyen, Y. Kitagawa, Y. Itoh, , T. Takeuchi

The paper develops Fc-modified SARS-CoV-2 neutralizing antibodies effective against variants, showing reduced viral titers and lung damage in animal models.

bioRxiv · Jun 21, 2022 · PreprintMicrobiology

Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2

H. Ohashi, T. Hishiki, D. Akazawa, K. S. Kim, J. Woo, K. Shionoya, K. Tsuchimoto, S. Iwanami, S. Moriyama, H. Kinoshita, S. Yamada, Y. Kuroda, T. Yamamoto, N. Kishida, S. Watanabe, , K. Watashi

The paper compares the efficacy of neutralizing antibodies and antiviral drugs against SARS-CoV-2 Omicron subvariants BA.1 and BA.2, finding differential responses to specific treatments.

bioRxiv · Feb 27, 2022Microbiology

Two doses of mRNA vaccine elicit cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant

R. Kotaki, Y. Adachi, S. Moriyama, T. Onodera, S. Fukushi, T. Nagakura, K. Tonouchi, K. Terahara, L. Sun, T. Takano, A. Nishiyama, M. Shinkai, K. Oba, F. Nakamura-Uchiyama, H. Shimizu, , Y. Takahashi

The paper shows that two doses of mRNA vaccine generate cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant, which are retained and contribute to enhanced antibody responses after a third dose.

bioRxiv · Dec 24, 2021 · PreprintImmunology

Ca2+-mediated higher-order assembly of b0,+AT-rBAT is a key step for system b0,+ biogenesis and cystinuria

Y. Lee, P. Wiriyasermkul, S. Moriyama, D. J. Mills, W. Kühlbrandt, S. Nagamori

This study identifies Ca2+-mediated higher-order assembly of b0,+AT-rBAT as critical for system b0,+ trafficking and reveals its role in type I cystinuria.

bioRxiv · May 6, 2021 · PreprintBiochemistry

Comparative analysis of antigen-specific anti-SARS-CoV-2 antibody isotypes in COVID-19 patients

H. Fujigaki, M. Inaba, M. Osawa, S. Moriyama, Y. Takahashi, T. Suzuki, K. Yamase, Y. Yoshida, Y. Yagura, T. Oyamada, M. Takemura, Y. Doi, K. Saito

This study compares antigen-specific antibody isotypes in COVID-19 patients to assess their kinetics, sensitivity, specificity, and correlation with neutralizing activity.

bioRxiv · Dec 4, 2020Immunology

A multi-hierarchical approach reveals D-serine as a hidden substrate of sodium-coupled monocarboxylate transporters

P. Wiriyasermkul, S. Moriyama, M. Suzuki, P. Kongpracha, N. Nakamae, S. Takeshita, Y. Tanaka, A. Matsuda, M. Miyasaka, K. Hamase, T. Kimura, M. Mita, J. Sasabe, S. Nagamori

The paper identifies two renal D-serine transport systems, revealing ASCT2 as a noncanonical substrate of SMCTs and highlighting their physiological and pathological roles.

bioRxiv · Aug 10, 2020Biochemistry