Author

R. M. Ruprecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. M. Carias· 2 shared E. J. Allen· 2 shared F. J. Villinger· 2 shared K. A. Rogers· 2 shared M. Arainga· 2 shared M. D. McRaven· 2 shared M. R. Anderson· 2 shared R. A. Taylor· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. M. Carias

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Author profile →

3 papers

Recent·Most cited

Localization of infection in neonatal rhesus macaques after oral viral challenge

T. J. Hope, R. A. Taylor, M. D. McRaven, A. M. Carias, M. R. Anderson, E. Matias, M. Arainga, E. J. Allen, K. A. Rogers, S. Gupta, V. Kulkarni, S. Lakhashe, R. Lorenzo-Redondo, Y. Thomas, A. Strickland, , R. M. Ruprecht

This study uses PET and fluorescent microscopy to track HIV distribution in neonatal rhesus macaques after oral challenge, showing virions localize to the rectal mucosa by four hours and the intestine contains the most infected cells at 96 hours.

PLOS Pathogens · Nov 18, 2021Peer-reviewedCell Biology

PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure

R. A. Taylor, S. Xiao, A. M. Carias, M. D. McRaven, D. N. Thakkar, M. Arainga, E. J. Allen, K. A. Rogers, S. C. Kumarapperuma, S. Gong, A. J. Fought, M. R. Anderson, Y. Thomas, J. R. Schneider, B. Goins, , T. J. Hope

The paper uses PET/CT and fluorescent microscopy to show dIgA increases HIV virion distribution and penetration in colorectal tissue and lymph nodes after exposure.

bioRxiv · Dec 23, 2020Cell Biology

Oral clade C SHIV challenge models to study pediatric HIV-1 infection by breastmilk transmission

K. K. A. Van Rompay, A. D. Curtis, M. G. Hudgens, R. Tuck, N. Choudhary, M. Dennis, R. Goswami, A. N. Nelson, J. D. Lifson, R. M. Ruprecht, G. M. Shaw, S. R. Permar, K. De Paris

This paper evaluates three clade C SHIVs for oral transmission and infection in infant rhesus macaques, finding varied chronic viremia levels and seroconversion thresholds.

bioRxiv · Feb 11, 2019 · PreprintMicrobiology