Author

R. Radhakrishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. F. Long· 1 shared A. M. Leidal· 1 shared a. malavia· 1 shared A. P. Wiita· 1 shared B. Yang· 1 shared C. Eng· 1 shared C. Stashko· 1 shared D. Ansari· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCell Biology

A. F. Long

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Author profile →

3 papers

Recent·Most cited

HIV-differentiated metabolite N-Acetyl-L-Alanine dysregulates human natural killer cell responses to Mycobacterium tuberculosis infection

B. Yang, T. Mukherjee, R. Radhakrishnan, P. Paidipally, D. Ansari, S. John, R. Vankayalapati, D. Tripathi, G. Yi

The paper identifies N-Acetyl-L-Alanine as a metabolite dysregulated by HIV that inhibits NK cell responses to Mycobacterium tuberculosis infection.

International Journal of Molecular Sciences · Apr 14, 2023Peer-reviewedImmunology

Physiologically Based Multiphysics Pharmacokinetic Model for Determining the Temporal Biodistribution of Targeted Nanoparticles

e. glass, S. Kulkarni, C. Eng, s. feng, a. malavia, R. Radhakrishnan

This paper develops and validates physics-based multiscale PBPK models for NP biodistribution, showing model B better matches experimental data and demonstrating neural networks can solve ODE systems with quasi-steady-state approximation.

bioRxiv · Mar 7, 2022 · PreprintBioengineering

ECM dimensionality tunes actin tension to modulate the endoplasmic reticulum and spheroid phenotype

F. Kai, G. Ou, R. W. Tourdot, C. Stashko, G. Gaietta, M. F. Swift, N. Volkmann, A. F. Long, Y. Han, H. H. Huang, J. J. Northey, A. M. Leidal, V. Viasnoff, D. M. Bryant, W. Guo, , V. M. Weaver

The paper shows that ECM dimensionality affects actin tension, which in turn modulates endoplasmic reticulum function and spheroid resilience in mammary epithelial cells.

bioRxiv · Jul 14, 2021 · PreprintCell Biology