Author

Ruwayhida Thebus

University of Cape Town

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:human· 4 Assay:DNA methylation· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Carolyn E. WilliamsoniD· 5 shared Anna YsseliD· 4 shared Dylan H. WestfalliD· 4 shared James I. MullinsiD· 4 shared Michal JuraskaiD· 4 shared Alec P. PankowiD· 3 shared Allan C. deCampiD· 3 shared Ben MurrelliD· 3 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersMicrobiology

Carolyn E. WilliamsonORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Long-Read Deep Sequencing Reveals High Rates of Multilineage Transmission and Rapid Viral Population Changes in Acute HIV Infection

James I. Mullins, Wenjie Deng, Elena E. Giorgi, Craig A. Magaret, Morgane Rolland, Tanmoy Bhattacharya A, Dylan H. Westfall, Anna Yssel, Roger E. Bumgarner, Ben Murrell, Thumbi Ndung’u, Merlin Lee Robb, Raabya Rossenkhan, Paul T. Edlefsen, Krista L. Dong, , Carolyn E. Williamson

The paper uses long-read sequencing to study HIV transmission and population dynamics in acute infection, finding high multilineage transmission rates and rapid viral evolution.

Nature Communications · May 25, 2026Peer-reviewedMicrobiology

Influence of the broadly neutralizing antibody VRC01 on HIV breakthrough virus populations in antibody-mediated prevention trials

Carolyn E. Williamson, Chivonne Moodley, Craig A. Magaret, Elena E. Giorgi, Morgane Rolland, Dylan H. Westfall, Anna Yssel, Wenjie Deng, Raabya Rossenkhan, Nonhlanhla N. Mkhize, Lennie Chen, Hong Zhao, Tanmoy Bhattacharya A, Alec P. Pankow, Ben Murrell, , James I. Mullins

The paper analyzes HIV breakthrough virus populations in antibody-mediated prevention trials, finding high rates of multilineage infections and recombination under VRC01 treatment.

Nature Communications · Apr 3, 2026Peer-reviewedMolecular Biology

VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials

Carolyn E. Williamson, Lyle Curry, Nonhlanhla N. Mkhize, Elena E. Giorgi, Craig A. Magaret, Bronwen E. Lambson, Sinethemba Bhebhe, Haajira Kaldine, Thandeka Moyo-Gwete, Morgane Rolland, Raabya Rossenkhan, Nina Marie G. Garcia, Chivonne Moodley, Anna Yssel, Yunda Huang, , James I. Mullins

This study identifies VRC01-mediated viral escape mutations in HIV-infected participants from antibody-mediated prevention trials, showing that VRC01 can select for escape variants with cross-resistance to other CD4bs bnAbs.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology

Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development

Maria C. Hesselman, Marius Zeeb, Peter Rusert, Chloé Pasin, Jennifer L. Mamrosh, Samuel Mundia Kariuki, Ian Pichler, Michèle Sickmann, Masako M. Kaufmann, Daniel G. Schmidt, Nikolas Friedrich, Karin Jutta Metzner, Audrey Rindler, Herbert Kuster, Craig H. Adams, , Alexandra Trkola

The paper identifies rare twin cysteine residues in HIV-1 Env V1 linked to neutralization escape and breadth development.

Cell Host & Microbe · Feb 1, 2025Peer-reviewedImmunology

HIV-1 Rebound Virus Consists of a Small Number of Lineages That Entered the Reservoir Close to ART Initiation

Lynn Tyers, Matthew Moeser, Jean Felistas Ntuli, Shuntai Zhou, E. Spielvogel, Amy Sondgeroth, Craig H. Adams, Ruwayhida Thebus, Anna Yssel, Salim S. Abdool Karim, Nigel Garrett, Sergei L. Kosakovsky Pond, Carolyn E. Williamson, Ronald I. Swanstrom, Melissa-Rose Abrahams, Sarah Joseph

The paper identifies that HIV-1 rebound virus primarily originates from a small number of lineages that entered the reservoir near ART initiation, despite the reservoir containing older sequences.

bioRxiv · Jan 29, 2025 · PreprintMicrobiology