Author

S. B. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. B. Hartono· 1 shared A. J. W. Lui· 1 shared B. H. Son· 1 shared C. A. Pratilas· 1 shared D. Gao· 1 shared E. de Stanchina· 1 shared E. Gladstone· 1 shared E. J. Lee· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. B. Hartono

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting Ribosome Biogenesis as a Novel Therapeutic Approach to Overcome EMT-related Chemoresistance in Breast Cancer.

Y. Ban, Y. Zou, Y. Liu, S. B. Lee, R. B. Bednarczyk, J. Sheng, Y. Cao, S. T. C. Wong, D. Gao

This study identifies ribosome biogenesis as a key driver of EMT/MET transitions in breast cancer and shows that targeting this pathway enhances chemotherapy efficacy against chemoresistant tumors.

bioRxiv · Jun 28, 2023Cancer Biology

Establishment of multiple novel patient-derived models of desmoplastic small round cell tumor enabling functional characterization of ERBB pathway signaling and pre-clinical evaluation of a novel targeted therapy approach

R. S. Smith, I. Odintsov, Z. Liu, T. Hayashi, A. J. W. Lui, M. Vojnic, Y. Suehara, M. S. Mattar, J. Hmeljak, H. A. Ramirez, M. Shaw, G. Bui, A. B. Hartono, E. Gladstone, H. Magnan, , R. Somwar

This study develops new DSRCT models and shows that targeting the ERBB pathway with EGFR inhibitors reduces tumor growth in preclinical models.

bioRxiv · Sep 22, 2020 · PreprintCancer Biology

Targeted Eicosanoid Profiling Reveals MicroRNA-155 Shifts PGE2/PGD2 Balance Towards Oncogenic State

S. Kim, E. S. Lee, E. J. Lee, J. Y. Jung, S. B. Lee, H. J. Lee, J. Kim, H. J. Kim, J. W. Lee, B. H. Son, G.-Y. Gong, S.-H. Ahn, S. Chang

This study shows miR-155 shifts PGE2/PGD2 balance towards an oncogenic state by regulating enzymes involved in prostaglandin synthesis.

bioRxiv · Apr 8, 2020 · PreprintCancer Biology