Author

S. Bullers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

E. H. Mann· 2 shared M. Friedrich· 2 shared A. Easton· 1 shared A. Geremia· 1 shared A. L. Corbin· 1 shared B. M. Kessler· 1 shared C. Pearson· 1 shared C.-P. Hackstein· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

E. H. Mann

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3 papers

Recent·Most cited

A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

C.-P. Hackstein, D. Costigan, L. Drexhage, C. Pearson, S. Bullers, N. Ilott, H. D. Akther, Y. Gu, M. E. B. FitzPatrick, O. J. Harrison, L. C. Garner, E. H. Mann, S. Pandey, M. Friedrich, N. M. Provine, , E. E. Thornton

The paper identifies a conserved population of MHC-II restricted, innate-like T cells in the gut of humans and mice that react to commensals and are implicated in colitis.

bioRxiv · Sep 26, 2022 · PreprintImmunology

IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease

M. Friedrich, M. Pohin, M. A. Jackson, I. Korsunsky, S. Bullers, K. Rue-Albrecht, Z. Christoforidou, D. Santhananthan, R. Ravindran, R. Sanches Peres, H. Sharpe, K. Wei, G. F. M. Watts, E. H. Mann, A. Geremia, , F. M. Powrie

bioRxiv · Feb 5, 2021 · PreprintImmunology

PYK2 controls intestinal inflammation via activation of IRF5 in macrophages

G. Ryzhakov, H. Almuttaqi, A. L. Corbin, T. Khoyratty, D. Berthold, S. Bullers, H. L. Eames, Z. Ai, S. Bonham, R. Fischer, L. Jostins-Dean, S. P. L. Travis, B. M. Kessler, I. A. Udalova

This study identifies PYK2 as a key regulator of intestinal inflammation by activating IRF5 in macrophages, showing reduced inflammation in colitis models and human ulcerative colitis biopsies.

bioRxiv · May 24, 2020 · PreprintImmunology