Author

S. C. Boggess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

B. Siemons· 2 shared E. W. Miller· 2 shared N. Huebsch· 2 shared V. Charwat· 2 shared A. Edwards· 1 shared A. Laemmle· 1 shared A. M. M. Gest· 1 shared A. Stahl· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersBioengineering

B. Siemons

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Author profile →

3 papers

Recent·Most cited

A red-emitting carborhodamine for monitoring and measuring membrane potential

A. M. M. Gest, J. R. Lazzari-Dean, G. Ortiz, S. K. Yaeger-Weiss, S. C. Boggess, E. W. Miller

This paper introduces a new red-emitting fluorescent indicator, CRhOMe, capable of both monitoring and measuring membrane potentials with improved signal-to-noise and quantification using fluorescence lifetime imaging microscopy.

bioRxiv · Oct 6, 2023Physiology

Metabolically-Driven Maturation of hiPSC-Cell Derived Heart-on-a-Chip

N. Huebsch, B. Charrez, B. Siemons, S. C. Boggess, S. Wall, G. Neiman, V. Charwat, K. Jaeger, F. L. T. Montiel, N. C. Jeffreys, N. Deveshwar, A. Edwards, J. Serrano, M. Snuderl, A. Stahl, , K. E. Healy

This study improves electrophysiological maturation of hiPSC-derived cardiomyocytes by combining metabolic cues and biophysical stimuli, revealing genotype-dependent responses to maturation media.

bioRxiv · Nov 14, 2020Bioengineering

Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction

F. T. Lee-Montiel, A. Laemmle, L. Dumont, C. S. Lee, N. Huebsch, V. Charwat, H. Okochi, M. J. Hancock, B. Siemons, S. C. Boggess, I. Goswami, E. Miller, H. Willenbring, K. Healy

The paper integrates hiPSC-based liver and heart microphysiological systems to predict drug-drug interactions, showing ketoconazole inhibits cisapride metabolism, causing arrhythmia in cardiac MPSs.

bioRxiv · May 24, 2020 · PreprintBioengineering