Author

L. Dumont

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Ardeshir· 1 shared A. Jain· 1 shared A. Laemmle· 1 shared A. M. Allen· 1 shared A. Verma· 1 shared A.-A. Dumont· 1 shared B. Schmidt· 1 shared B. Siemons· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. A. Ardeshir

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

K. K. A. Van Rompay, K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, J. W. Roh, A. Verma, Y. Shaan Lakshmanappa, B. Schmidt, C. Di Germanio, N. Rizvi, M. Stone, G. Simmons, , J. R. Reader

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

bioRxiv · Sep 1, 2021 · PreprintImmunology

Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role

A.-A. Dumont, L. Dumont, D. Zhou, H. Giguere, C. Pileggi, M.-E. Harper, D. P. Blondin, M. S. Scott, M. Auger-Messier

This study shows that deleting Srsf3 in cardiomyocytes leads to mitochondrial dysfunction, reduced survival, and cardiac remodeling in mice.

bioRxiv · Jul 3, 2020Physiology

Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction

F. T. Lee-Montiel, A. Laemmle, L. Dumont, C. S. Lee, N. Huebsch, V. Charwat, H. Okochi, M. J. Hancock, B. Siemons, S. C. Boggess, I. Goswami, E. Miller, H. Willenbring, K. Healy

The paper integrates hiPSC-based liver and heart microphysiological systems to predict drug-drug interactions, showing ketoconazole inhibits cisapride metabolism, causing arrhythmia in cardiac MPSs.

bioRxiv · May 24, 2020 · PreprintBioengineering

The metabolic repair enzyme phospho-glycolate phosphatase regulates central carbon metabolism and fosmidomycin sensitivity in Plasmodium falciparum

L. Dumont, M. B. Richardson, P. van der Peet, M. W. Dixon, S. J. Williams, M. J. McConville, L. Tilley, S. Cobbold

This study identifies phospho-glycolate phosphatase (PfPGP) as a regulator of central carbon metabolism in Plasmodium falciparum, showing its role in metabolite homeostasis and drug sensitivity.

bioRxiv · Sep 12, 2018Biochemistry