Author

S. Chukkapalli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. A. Newman· 2 shared A. M. Lerario· 1 shared B. Yu· 1 shared C. Gonzalez del Rey· 1 shared C. LaPensee· 1 shared D. E. Conway· 1 shared D. J. Sykes· 1 shared D. R. Mohan· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

E. A. Newman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural enrichment attenuates colitis-associated colon cancer

D. J. Sykes, S. Solanki, S. Chukkapalli, K. Williams, E. A. Newman, K. Resnicow, Y. M. J. Shah

The paper investigates how enriched versus impoverished housing conditions affect tumorigenesis in a mouse model of colitis-associated colon cancer, finding enriched housing reduces tumor burden.

bioRxiv · Feb 13, 2024 · PreprintCancer Biology

Targeting oncogenic Wnt/β-catenin signaling in adrenocortical carcinoma disrupts ECM expression and impairs tumor growth.

M. K. Penny, A. M. Lerario, K. J. Basham, S. Chukkapalli, Y. Yu, D. R. Mohan, C. LaPensee, K. Converso-Baran, M. Hoenerhoff, L. Suarez Fernandez, C. Gonzalez del Rey, T. J. Giordano, R. Han, E. A. Newman, G. D. Hammer

This paper identifies a Wnt/β-catenin-regulated extracellular matrix (ECM) program in adrenocortical carcinoma (ACC) that promotes tumor growth and shows that inhibiting this pathway reduces tumor viability and growth in preclinical models.

bioRxiv · Oct 23, 2022Cancer Biology

Rho activation drives luminal collapse and eversion in epithelial acini

V. Narayanan, P. Purkayastha, B. Yu, K. Pendyala, S. Chukkapalli, J. I. Cabe, R. B. Dickinson, D. E. Conway, T. P. Lele

This study shows that RhoA activation causes apical-out eversion in epithelial acini by altering mechanical homeostasis and surface tension differences.

bioRxiv · Jul 6, 2022Biophysics