Author

S. M. Ahmed

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Addhya· 1 shared A. Antonopoulos· 1 shared A. Dell· 1 shared A. E. Friedman· 1 shared Adnan HalimiD· 1 shared Borja Ochoa-LizarraldeiD· 1 shared C. Chua· 1 shared C. Gradinaru· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Addhya

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure and mechanism of the human TMEM260 O-mannosyltransferase

Javier O. Cifuente, Lorenzo Povolo, Borja Ochoa-Lizarralde, S. M. Ahmed, Sergey Y. Vakhrushev, Jorge Pedro López-Alonso, Igor Tascón, Javier Fernández-Martı́nez, Hiren Jitendra Joshi, Adnan Halim, Iban Ubarretxena‐Belandia

This study determines the cryo-EM structure of human TMEM260, revealing its mechanism for O-mannosylation of key receptors and providing insights into related congenital disorders.

bioRxiv · Mar 17, 2026 · PreprintBiophysics

Efficient Inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc

S.-S. Wang, V. del Solar, X. Yu, A. Antonopoulos, A. E. Friedman, K. Agarwal, M. Garg, S. M. Ahmed, A. Addhya, M. Nasirikenari, J. T. Lau, A. Dell, S. M. Haslam, S.-G. Sampathkumar, S. Neelamegham

This paper demonstrates that Ac5GalNTGc is a potent inhibitor of O-glycan biosynthesis, effectively reducing O-glycan elongation and modulating leukocyte functions.

bioRxiv · Dec 13, 2020Biochemistry

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

S. M. Ahmed, P. D. Ramani, S. Q. R. Wong, X. Zhao, R. Ivanyi-Nagy, T. C. Leong, C. Chua, Z. Li, H. Hentze, I. B. Tan, J. Yan, R. DasGupta, P. Droge

This paper identifies HMGA2 as a regulator of DNA supercoiling and replication fork stability, showing its protective role against DNA damage from topoisomerase poisons and its potential as a therapeutic marker in cancer.

bioRxiv · Feb 8, 2019Cancer Biology

Exocyst Dynamics During Vesicle Tethering and Fusion

S. M. Ahmed, H. Nishida-Fukuda, Y. Li, W. H. McDonald, C. Gradinaru, I. G. Macara

This study investigates exocyst dynamics in mammalian cells, revealing tetrameric subcomplexes that dynamically associate with vesicles and plasma membrane.

bioRxiv · Aug 3, 2018Cell Biology