Author

S. M. McCarty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

J. Z. Sexton· 3 shared C. E. Wobus· 2 shared C. J. Zhang· 2 shared C. Mirabelli· 2 shared J. W. Wotring· 2 shared M. J. O'Meara· 2 shared R. Fursmidt· 2 shared S. K. Handelman· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

J. Z. Sexton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In Vitro Evaluation and Mitigation of Niclosamide's Liabilities as a COVID-19 Treatment.

J. W. Wotring, S. M. McCarty, K. Shafiq, C. J. Zhang, T. Nguyen, S. R. Meyer, R. Fursmidt, C. Mirabelli, M. C. Clasby, C. E. Wobus, M. J. O'Meara, J. Z. Sexton

This study evaluates niclosamide's limitations as a COVID-19 treatment and identifies analogs with improved potency and reduced toxicity.

bioRxiv · Jun 24, 2022Microbiology

Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19

C. Mirabelli, J. W. Wotring, C. J. Zhang, S. M. McCarty, R. Fursmidt, T. Frum, N. S. Kadambi, A. T. Amin, T. R. O'Meara, C. D. Pretto-Kernahan, J. R. Spence, J. Huang, K. D. Alysandratos, D. N. Kotton, S. K. Handelman, , J. Z. Sexton

This study identifies 17 FDA-approved compounds with antiviral efficacy against SARS-CoV-2 using high-throughput screening and finds lactoferrin as a promising drug candidate with multiple antiviral mechanisms.

Proceedings of the National Academy of Sciences · Aug 19, 2021Peer-reviewedCell Biology

Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity

R. B. Vohnoutka, A. Kuppa, Y. Hegde, Y. Chen, A. Pant, E.-Y. K. Choi, S. M. McCarty, D. Bagchi, X. Du, Y. Chen, V. L. Chen, L. F. Bielak, L. H. Maguire, S. K. Handelman, J. Z. Sexton, , E. K. Speliotes

This study shows that knocking out Lyplal1 in mice leads to sex-specific protection against diet-induced obesity, mirroring human genetic findings.

bioRxiv · Aug 5, 2021Biochemistry