S. McCarthy

Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation

This study examines two Neotropical butterfly radiations, revealing high rates of hybridization and chromosomal rearrangements as drivers of diversification.

Delta-Conotoxin Structure Prediction and Analysis through Large-scale Comparative and Deep Learning Modeling Approaches

This study uses AlphaFold and RosettaCM to model 18 uncharacterized delta-conotoxins, providing structural insights and implications for drug development.

The sensory shark: high-quality morphological, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates

This study integrates genomic, transcriptomic, and morphological data from the small-spotted catshark to uncover molecular mechanisms underlying sensory organ evolution in jawed vertebrates.

An integrative characterisation of proline cis and trans conformers in a disordered peptide

This paper uses MD simulations, NMR, and SAXS to characterise the cis and trans proline conformations of ORF6CTR from SARS-CoV-2, showing good agreement between simulations and experiments.

Genomic evidence reveals three sequential W-autosome fusions in Heliconius butterflies

The paper identifies three sequential W-autosome fusions in Heliconius butterflies, revealing their role in adaptive radiation and sex chromosome evolution.

Caecilian genomes reveal molecular basis of adaptation and convergent evolution of limblessness in snakes and caecilians.

The paper analyzes caecilian genomes to identify molecular mechanisms underlying limblessness and convergent evolution with snakes, finding shared genetic targets involved in limb development.

Genomic consequences of domestication of the Siamese fighting fish

The paper uses genomic data to show betta fish were domesticated over 1,000 years ago and identifies genes involved in their phenotypic diversity.

REGEN-COV protects against viral escape in preclinical and human studies

This study shows that REGEN-COV, a combination of non-competing antibodies, provides broad coverage against SARS-CoV-2 variants and prevents the emergence of new variants in clinical and preclinical settings.