Author

S. Mitoma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:chicken / avian· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Saito· 2 shared A. Hoshino· 1 shared A. Takada· 1 shared D. Yamasoba· 1 shared E. Hara· 1 shared E. Urano· 1 shared F. Sugihara· 1 shared G. Schreiber· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Saito

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An engineered ACE2 decoy broadly neutralizes Omicron subvariants and shows therapeutic effect in SARS-CoV-2-infected cynomolgus macaques

E. Urano, Y. Itoh, T. Suzuki, T. Sasaki, J.-i. Kishikawa, K. Akamatsu, Y. Higuchi, Y. Sakai, T. Okamura, S. Mitoma, F. Sugihara, A. Takada, M. Kimura, M. Hirose, T. Sasaki, , T. Okamoto

This paper shows an engineered ACE2 decoy neutralizes Omicron subvariants and is effective in treating SARS-CoV-2 infection in macaques.

bioRxiv · Dec 29, 2022 · PreprintMicrobiology

Identifying Pathogen and Allele Type Simultaneously (IPATS) in a single well using droplet digital PCR

K. Notsu, H. El Daous, S. Mitoma, X. Wu, J. Norimine, S. Sekiguchi

The paper develops a single-well droplet digital PCR method to simultaneously detect pathogen and host allele types, showing DRB3*009:02 alleles suppress BLV proviral load.

bioRxiv · Sep 10, 2022Microbiology

Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5

I. Kimura, D. Yamasoba, T. Tamura, N. Nao, Y. Oda, S. Mitoma, J. Ito, H. Nasser, J. Zahradnik, K. Uriu, S. Fujita, Y. Kosugi, L. Wang, M. Tsuda, M. Kishimoto, , K. Sato

This study analyzes the virological characteristics of SARS-CoV-2 Omicron variants BA.2.12.1, BA.4, and BA.5, finding they have higher reproduction numbers, reduced neutralization by prior immunity, increased replication in lung cells, and greater pathogenicity in hamsters compared to BA.2.

bioRxiv · May 26, 2022Microbiology