Author

M. Kishimoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 7 Approach:experimental assay· 6 Organism:human· 3 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Sawa· 4 shared M. Sasaki· 4 shared Y. Orba· 4 shared D. Yamasoba· 3 shared H. Ito· 3 shared I. Kimura· 3 shared J. Ito· 3 shared K. Matsuno· 3 shared

Activity by Year

2022-2023 · peak 7/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMicrobiology

H. Sawa

Mutual co-authors in cluster

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8 papers

Recent·Most cited

Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in severe COVID-19

M. Sasaki, S. Iida, Y. Hirata, S. Kusakabe, K. Konishi, Y. Itakura, K. Tabata, M. Kishimoto, H. Kobayashi, T. Ariizumi, K. Intaruck, H. Nobori, S. Toba, A. Sato, K. Matsuno, , H. Sawa

This study shows that combining an oral antiviral with a corticosteroid improves treatment outcomes in delayed SARS-CoV-2 infection in hamsters compared to monotherapy.

bioRxiv · Jun 20, 2023Microbiology

Morphogenesis of bullet-shaped rabies virus particles requires a functional interplay between the viral matrix protein and ESCRT-I component TSG101

Y. Itakura, K. Tabata, T. Saito, K. Intaruck, N. Kawaguchi, M. Kishimoto, S. Torii, S. Kobayashi, N. Ito, M. Harada, S. Inoue, K. Maeda, A. Takada, W. W. Hall, Y. Orba, , M. Sasaki

This study identifies the interaction between rabies virus matrix protein and TSG101 as essential for bullet-shaped virion formation and efficient budding.

bioRxiv · Dec 16, 2022Microbiology

Comparative pathogenicity of SARS-CoV-2 Omicron subvariants including BA.1, BA.2, and BA.5

T. Tamura, D. Yamasoba, Y. Oda, J. Ito, T. Kamasaki, N. Nao, R. Hashimoto, Y. Fujioka, R. Suzuki, L. Wang, H. Ito, I. Kimura, I. Yokota, M. Kishimoto, M. Tsuda, , T. Fukuhara

This study compares the pathogenicity of SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.5, finding BA.5 is more fusogenic and induces stronger inflammation than earlier variants.

bioRxiv · Aug 5, 2022Microbiology

Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5

I. Kimura, D. Yamasoba, T. Tamura, N. Nao, Y. Oda, S. Mitoma, J. Ito, H. Nasser, J. Zahradnik, K. Uriu, S. Fujita, Y. Kosugi, L. Wang, M. Tsuda, M. Kishimoto, , K. Sato

This study analyzes the virological characteristics of SARS-CoV-2 Omicron variants BA.2.12.1, BA.4, and BA.5, finding they have higher reproduction numbers, reduced neutralization by prior immunity, increased replication in lung cells, and greater pathogenicity in hamsters compared to BA.2.

bioRxiv · May 26, 2022Microbiology

A comprehensive list of the replication promoters of Bunyavirales reveals a unique promoter structure in Nairoviridae differing from other virus families

Y. Neriya, S. Kojima, A. Sakiyama, M. Kishimoto, T. Iketani, T. Watanabe, Y. Abe, H. Shimoda, K. Nakagawa, T. Koma, Y. Matsumoto

The paper identifies a unique GC-rich promoter structure in Nairoviridae, distinguishing it from other Bunyavirales families, and provides a comprehensive list of replication promoters.

bioRxiv · May 6, 2022Microbiology

Oral administration of S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and accelerates recovery from clinical aspects of COVID-19

M. Sasaki, K. Tabata, M. Kishimoto, Y. Itakura, H. Kobayashi, T. Ariizumi, K. Uemura, S. Toba, S. Kusakabe, Y. Maruyama, S. Iida, N. Nakajima, T. Suzuki, S. Yoshida, H. Nobori, , H. Sawa

This study shows that oral S-217622 reduces SARS-CoV-2 viral load and improves recovery in hamsters, with activity against multiple variants.

bioRxiv · Feb 14, 2022Microbiology

Virological characteristics of SARS-CoV-2 BA.2 variant

D. Yamasoba, I. Kimura, H. Nasser, Y. Morioka, N. Nao, J. Ito, K. Uriu, M. Tsuda, J. Zahradnik, K. Shirakawa, R. Suzuki, M. Kishimoto, Y. Kosugi, K. Kobiyama, T. Hara, , Sawa

This study compares the virological characteristics of SARS-CoV-2 BA.2 and BA.1 variants, finding BA.2 has higher transmissibility, different antigenicity, greater replicative capacity, and higher pathogenicity in hamsters.

bioRxiv · Feb 14, 2022Microbiology

Frequency of a nucleotide overhang at the 5' end of hemorrhagic fever mammarenavirus genomes in public sequence data

Y. Neriya, S. Kojima, M. Kishimoto, A. Sakiyama, T. Iketani, T. Watanabe, Y. Abe, H. Shimoda, K. Nakagawa, T. Koma, Y. Matsumoto

The paper examines the frequency of a 5' guanine overhang in mammarenavirus genomes and links it to their pathogenicity.

bioRxiv · Feb 4, 2022 · PreprintMicrobiology