Memory B cell Development in Response to mRNA SARS-CoV-2 and Nanoparticle Immunization in Mice
Marie Wiatr, zijun wang, Marie Canis, Brianna Hernandez, Anna Gazumyan, Gabriela S. Silva Santos, Sadman Shawraz, Songhee lee, Paul D. Bieniasz, Théodora Hatziioannou, Frauke Muecksch, Michel C. Nussenzweig
This study compares memory B cell responses to mRNA and nanoparticle vaccines in mice, finding similar antibody sequences but better breadth from mosaic nanoparticle vaccines.
Proceedings of the National Academy of Sciences · Jan 2, 2026Peer-reviewedImmunology