Sam Seid

Increased activity without changes in coupling between somata and apical dendrites during visual mismatches

This study examines neural responses in mouse visual cortex to natural and artificial visual stimuli, finding increased activity in response to natural mismatches but no change in dendritic-somatic coupling.

Learning from unexpected events in the neocortical microcircuit

The paper shows that cortical pyramidal neurons exhibit distinct unexpected event signals in somata and distal apical dendrites that change over days, suggesting a role in hierarchical computation.

Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

The paper shows that visual areas differentially encode temporal context and expectation in natural scenes, with representational drift observed in lower areas but not higher ones.

Stimulus novelty uncovers coding diversity in survey of visual cortex

The paper identifies diverse functional neuron types in the visual cortex that process novel and familiar stimuli in mice.

A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex

The paper maps brain-wide monosynaptic inputs to specific neuron classes in mouse visual cortex using an improved rabies virus tracing strategy and identifies connectivity patterns within and between visual areas.

Measuring stimulus-evoked neurophysiological differentiation in distinct populations of neurons in mouse visual cortex

The paper measures stimulus-evoked neurophysiological differentiation in mouse visual cortex neurons across layers and areas, finding greater differentiation in specific layers and areas for unscrambled stimuli.

A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas

The paper presents a dataset and analysis of spiking activity across multiple mouse visual areas, revealing that functional connectivity mirrors anatomical hierarchy.

A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex

The paper presents a large-scale dataset of neural activity in the mouse visual cortex and shows that responses to different stimuli are largely independent, suggesting multi-layer hierarchical computation.

VIP interneurons selectively enhance weak but behaviorally-relevant stimuli.

The paper shows VIP interneurons in mouse visual cortex have complementary contrast tuning to SST neurons and synergistically respond to visual motion and locomotion, enhancing behaviorally-relevant stimuli while maintaining network stability.

Remote focusing system for simultaneous dual-plane mesoscopic multiphoton imaging

The paper introduces a dual-plane mesoscopic imaging system that improves imaging throughput by combining temporal-division multiplexing and remote focusing.