Author

Evelyn Chukwurah

Case Western Reserve UniversityORCID 0000-0002-9706-7003Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandra TrifunovićiD· 1 shared Allison M. Culver· 1 shared Andrew Caleb HsiehiD· 1 shared Anna M. BagnelliD· 1 shared Austin J. Smith· 1 shared Bo‐Jhih Guan· 1 shared Carin M. PapendorpiD· 1 shared Chien-Wen CheniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Aleksandra TrifunovićORCID

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2 papers

Recent·Most cited

Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress

Raul Jobava, Yuanhui Mao, Bo‐Jhih Guan, Di Hu, Dawid Krokowski, Chien-Wen Chen, Xin Erica Shu, Evelyn Chukwurah, Jing Wu, Zhaofeng Gao, Leah L. Zagore, William C. Merrick, Aleksandra Trifunović, Andrew Caleb Hsieh, Saba Valadkhan, , Maria Hatzoglou

The paper shows that cells use an adaptive pausing response to survive severe stress by pausing translation and limiting ATP use, followed by recovery through ISR signaling.

Molecular Cell · Oct 1, 2021Peer-reviewedMolecular Biology

ASH1L REGULATES THE STRUCTURAL DEVELOPMENT OF NEURONAL CIRCUITRY BY MODULATING BDNF/TrkB SIGNALING IN HUMAN NEURONS

Seon Hye Cheon, Allison M. Culver, Anna M. Bagnell, Foster D. Ritchie, Janay M. Clytus, Mikayla M. McCord, Carin M. Papendorp, Evelyn Chukwurah, Austin J. Smith, Mara H. Cowen, Pankaj S. Ghate, Shannon William Davis, Judy Shih-Hwa Liu, Sofia B. Lizarraga

This study shows ASH1L regulates neuronal connectivity by modulating BDNF/TrkB signaling through its interaction with PRC2 in human neurons, linking ASH1L mutations to autism pathogenesis.

bioRxiv · Feb 18, 2020 · PreprintNeuroscience