Author

Jaynish S. Shah

The Alfred HospitalORCID 0000-0002-1089-7355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrian V. LeeiD· 1 shared Alexander J. ColeiD· 1 shared Ali G. TurhaniD· 1 shared Allison C. SharrowiD· 1 shared Alyssa M. WieldiD· 1 shared Amanda M. ClarkiD· 1 shared Bijay P. DhungeliD· 1 shared Charles G. BaileyiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrian V. LeeORCID

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3 papers

Recent·Most cited

Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer.

Santiago Panesso-Gómez, Alexander J. Cole, Alyssa M. Wield, Vivian I. Anyaeche, Jaynish S. Shah, Qi Jiang, Tonge Ebai, Allison C. Sharrow, George C. Tseng, Euisik Yoon, Daniel D. Brown, Amanda M. Clark, Scott D. Larsen, Ian Eder, David M. Gau, , Ronald J. Buckanovich

This study identifies the MRTFA/SRF pathway as a regulator of quiescence in cancer and shows that inhibiting it induces quiescence and reduces tumor growth.

bioRxiv · Nov 15, 2024 · PreprintCancer Biology

Massively Parallel Dissection of RNA in RNA-protein interactions in vivo

Yu Hsuan Lee, Evan P. Hass, William Campodonico-Burnett, Yong Kyu Lee, Erika L. Lasda, Jaynish S. Shah, John L. Rinn, Taeyoung Hwang

The paper introduces MPRNA-IP, a method to dissect RNA-protein interactions in vivo using custom RNA pools and statistical models to identify binding domains and structures.

Nucleic Acids Research · May 10, 2024Peer-reviewedGenomics

Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukemia patients

Ulf Schmitz, Jaynish S. Shah, Bijay P. Dhungel, Geoffray Monteuuis, Phuc‐Loi Luu, Veronika Petrova, Cynthia Metierre, Shalima S. Nair, Charles G. Bailey, Verity A Saunders, Ali G. Turhan, Deborah L. White, Susan Branford, Susan J. Clark, Timothy P. Hughes, , John E.J. Rasko

The paper shows that chronic myeloid leukemia patients in molecular remission still have widespread aberrant alternative splicing, unlike normal gene expression and DNA methylation patterns.

Cancers · Dec 11, 2020Peer-reviewedGenetic & Genomic Medicine