Author

Shanshan He

Nanostring Technologies (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Jason ReevesiD· 2 shared Michael J. Patrick· 2 shared Adam L. Essene· 1 shared Alex K. ShalekiD· 1 shared Alexander SturmiD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Amit Dipak AminiD· 1 shared Andriy Myloserdnyy· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Jason ReevesORCID

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Author profile →

2 papers

Recent·Most cited

The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer

Peter L. Wang, Nicole A. Lester, Ella N. Perrault, Jennifer Su, Dennis H. Gong, Carina Shiau, Jingyi Cao, Phuong Trang Nguyen, Jung Woo Bae, Deniz Olgun, Hannah I. Hoffman, Ashley Lam, Jean Huang-Gao, Saifur Rahaman, Jimmy A. Guo, , William L. Hwang

This study identifies Pdgfd-Pdgfrb signaling as a driver of perineural invasion in pancreatic cancer by promoting cancer cell invasiveness and nerve engagement.

bioRxiv · Aug 26, 2025 · PreprintCancer Biology

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

Yered H. Pita-Juárez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni Marie Delorey, Adam L. Essene, Olga Rachel Brook, Deepti B. Pant, Disha Skelton-Badlani, Pourya Naderi Yeganeh, Pinzhu Huang, Liuliu Pan, TYLER D. HETHER, Tallulah S. Andrews, , Ioannis S. Vlachos

This study creates a single-nucleus and spatial transcriptomic atlas of the COVID-19 liver, revealing cellular and functional disruptions associated with organ damage.

Genome biology · Mar 14, 2025Peer-reviewedGenomics