Author

Skye R. Rudiger

South Australian Research and Development Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christopher Simon BawdeniD· 2 shared Russell G. SnelliD· 2 shared Ake Tzu-Hui LuiD· 1 shared Amin HaghaniiD· 1 shared Andrew JiangiD· 1 shared Clive J. McLaughlan· 1 shared Donna M. BondiD· 1 shared Henry John WaldvogeliD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Christopher Simon BawdenORCID

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2 papers

Recent·Most cited

Evidence for glutamate excitotoxicity that occurs before the onset of striatal cell loss and motor symptoms in an ovine Huntington's Disease model.

Andrew Jiang, Linya You, Renée R. Handley, Victoria Hawkins, Suzanne J. Reid, Jessie C. Jacobsen, Stefano Patassini, Skye R. Rudiger, Clive J. McLaughlan, Jennifer M. Kelly, Paul John Verma, Christopher Simon Bawden, James F. Gusella, Marcy E. MacDonald, Henry John Waldvogel, , Russell G. Snell

The paper identifies transcriptional upregulation of glutamate receptors and downregulation of oxidative phosphorylation in an ovine HD model before neuronal loss and motor symptoms.

bioRxiv · Jun 20, 2023 · PreprintNeuroscience

Castration delays epigenetic aging and feminises DNA methylation at androgen-regulated loci

Victoria J Sugrue, Joseph Alan Zoller, Pritika J. Narayan, Ake Tzu-Hui Lu, Oscar Ortega‐Recalde, Matthew J. Grant, Christopher Simon Bawden, Skye R. Rudiger, Amin Haghani, Donna M. Bond, Reuben R Hore, Michael Garratt, Karen E. Sears, Nan Wang, X. William Yang, , Steve Horvath

This study develops an epigenetic clock for sheep and finds that castration slows aging and feminizes DNA methylation at androgen-regulated loci.

eLife · Jun 28, 2021Peer-reviewedDevelopmental Biology