Titin-dependent biomechanical feedback tailors sarcomeres to specialised muscle functions in insects
Vincent Loreau, Wouter H. Koolhaas, Eunice HoYee Chan, Paul de Boissier, Nicolas Brouilly, Sabina Avosani, Aditya Sane, Christophe Pitaval, Stefanie Reiter, Nuno Miguel Luis, Pierre J.J. Mangeol, Anne C. von Philipsborn, Jean-François Rupprecht, Dirk Görlich, Bianca Hermine Habermann, Frank Schnorrer
The paper identifies a titin-dependent biomechanical feedback mechanism that adjusts sarcomere structure to meet the functional demands of different insect muscle types.
bioRxiv · Sep 30, 2024 · PreprintDevelopmental Biology