Author

T. Fill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Rokas· 2 shared F. Almeida· 2 shared G. H. Goldman· 2 shared I. Malavazi· 2 shared M. C. Rocha· 2 shared P. A. de Castro· 2 shared T. F. dos Reis· 2 shared A. Brown· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersMicrobiology

A. Rokas

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deacetylation by sirtuins is important for Aspergillus fumigatus pathogenesis and virulence

N. S. Wassano, G. B. da Silva, A. H. Reis, J. A. Gerhardt, E. P. Antoniel, D. Y. Akiyama, C. P. Rezende, L. X. Neves, E. Vasconcelos, F. L. Figueiredo, F. Almeida, P. A. de Castro, C. F. Pinzan, G. Goldman, A. F. Paes Leme, , A. Damasio

This study shows that sirtuins in Aspergillus fumigatus are important for virulence and pathogenesis, with AfSirE deletion reducing virulence and altering protein acetylation and gene expression.

bioRxiv · Sep 25, 2023 · PreprintMicrobiology

Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin

A. C. Colabardini, F. Wang, Z. Dong, L. Pardeshi, M. C. Rocha, J. H. Costa, T. F. dos Reis, A. Brown, Q. Z. Jaber, M. Fridman, T. Fill, A. Rokas, I. Malavazi, K. H. Wong, G. H. Goldman

This study investigates transcriptional heterogeneity in Aspergillus fumigatus strains responding to caspofungin, identifying a core response and variable response linked to secondary metabolite biosynthesis and iron homeostasis.

bioRxiv · Jul 15, 2021Microbiology

Aspergillus fumigatus G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production, and virulence

A. P. da Costa Filho, G. T. Brancini, P. A. de Castro, J. A. Ferreira, L. P. Silva, M. C. Rocha, I. Malavazi, J. G. de Moraes Pontes, T. Fill, R. Silva, F. Almeida, J. L. Steenwyk, A. Rokas, T. F. dos Reis, L. N. Ries, G. H. Goldman

This paper investigates the role of GprM and GprJ GPCRs in A. fumigatus, showing they regulate cell wall integrity, secondary metabolite production, and virulence.

bioRxiv · Aug 3, 2020Microbiology