T. Gupta

Age-associated elevated inflammation and immune pathways in the mice heart are linked to Adiponectin-Adipor1-RelA signaling

This study identifies age-related inflammation in mouse hearts linked to Adiponectin-Adipor1-RelA signaling through gene expression, protein analysis, and functional experiments.

Conformational flexibility is a key determinant of the lytic activity of the pore forming protein, Cytolysin A

This study shows that conformational flexibility in the β-tongue and N-terminus regions of ClyA is essential for its lytic activity and membrane-mediated conformational transition.

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC

This study identifies the molecular mechanism of CPC-Sgo1 interaction and shows its role in centromere localization and function through structural and functional analyses.

Identification of novel pulmonary vein nodes as generators of ectopic arrhythmic foci for atrial fibrillation: An immuno-histochemical proof

The paper identifies novel pulmonary vein nodes as potential sources of ectopic arrhythmogenic foci in atrial fibrillation through immunohistochemical analysis of human tissue.

A highly conserved binding pocket on PP2A-B56 is required for shugoshin binding and cohesion protection

This study identifies a conserved binding pocket on PP2A-B56 essential for Sgo1 interaction and cohesion protection, showing that complex formation is not strictly required for cohesion protection.

Role of Rv3351c in trafficking Mycobacterium tuberculosis bacilli in alveolar epithelial cells and its contribution to disease

This study identifies Rv3351c as a M. tuberculosis protein that facilitates bacilli trafficking through alveolar epithelial cells by inducing lipid raft aggregation and reducing phagolysosome fusion.

Aggression and discrimination among closely versus distantly related species of Drosophila

This study investigates aggression between Drosophila species, finding that closely related species show equal aggression toward conspecifics and heterospecifics, while distantly related species are more aggressive toward conspecifics.

Disparate patterns of thermal adaptation between life stages in temperate vs. tropical Drosophila melanogaster

This study compares thermal tolerance in adult and embryonic stages of Drosophila melanogaster across temperate and tropical populations, finding no variation in adult tolerance but higher tropical embryonic tolerance.