Author

M. B. Weisser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. Nilsson· 4 shared A. Kettenbach· 3 shared B. Lopez-Mendez· 3 shared A. A. Jeyaprakash· 2 shared B. McEwan· 2 shared D. Garvanska· 2 shared G. Montoya· 2 shared T. Kruse· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

J. Nilsson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Substrate recognition principles for the PP2A-B55 protein phosphatase

T. Kruse, D. Garvanska, J. K. Varga, W. Garland, B. McEwan, J. Hein, M. B. Weisser, I. B. Puy, C. Chan, P. S. Parrila, B. Lopez-Mendez, A. A. Jeyaprakash, O. Schueler-Furman, T. H. Jensen, A. Kettenbach, J. Nilsson

The paper identifies conserved mechanisms by which PP2A-B55 substrates bind B55 through α-helices and develops a competitive inhibitor to study its function.

bioRxiv · Feb 10, 2024Cell Biology

SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection

D. Garvanska, R. E. Alvarado, F. Mundt, E. Nilsson, J. Duel, F. Coscia, R. Lindqvist, K. Lokugamage, B. Johnson, J. A. Plante, D. R. Morris, M. N. Vu, L. Estes, A. McLeland, J. Walker, , J. Nilsson

This study identifies a novel interaction between SARS-CoV-2 NSP3 and FMRPs, showing that this interaction is critical for viral replication and disease progression.

bioRxiv · Sep 1, 2023 · PreprintMicrobiology

Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting

G. Vit, J. Duro, G. Rajendraprasad, E. P. Hertz, L. Holland, M. B. Weisser, B. McEwan, B. Lopez-Mendez, G. Montoya, N. Mailand, K. Maeda, A. Kettenbach, J. Nilsson

This study challenges previous claims that iHAP1 and DT-061 target PP2A-B56 complexes, showing instead that they exert toxicity through microtubule disruption and ER/Golgi disruption, respectively.

bioRxiv · Jul 8, 2021Cell Biology

A highly conserved binding pocket on PP2A-B56 is required for shugoshin binding and cohesion protection

Y. Ueki, M. Hadders, M. B. Weisser, I. Nasa, T. Gupta, E. T. Hertz, T. Kruse, G. Montoya, A. A. Jeyaprakash, A. Kettenbach, S. M. A. Lens, J. Nilsson

This study identifies a conserved binding pocket on PP2A-B56 essential for Sgo1 interaction and cohesion protection, showing that complex formation is not strictly required for cohesion protection.

bioRxiv · Dec 18, 2020Cell Biology