Author

S. J. Wilson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 7 Organism:human· 6 Organism:multiple species· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Wickenhagen· 4 shared J. Hughes· 3 shared M. L. Turnbull· 3 shared M. Palmarini· 3 shared A. da Silva Filipe· 2 shared A. H. Patel· 2 shared A. Kohl· 2 shared E. Sugrue· 2 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersMicrobiology

A. Wickenhagen

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Zoonotic avian influenza viruses evade human BTN3A3 restriction

R. M. Pinto, S. Bakshi, S. Lytras, M. K. Zakaria, S. Swingler, J. C. Worrell, V. Herder, M. Varjak, N. Cameron-Ruiz, M. Collados-Rodriguez, M. Varela, A. Wickenhagen, C. Loney, Y. Pei, J. Hughes, , M. Palmarini

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology

A human and rhesus macaque interferon-stimulated gene screen reveals ARHGEF3/XPLN as an antiviral gene against hepatitis C virus and other flaviviruses

C. Bamford, E. Aranday-Cortes, R. Sanchez-Velazquez, C. Mullan, A. Kohl, A. H. Patel, S. J. Wilson, J. McLauchlan

This study identifies ARHGEF3/XPLN as an antiviral gene that inhibits HCV and flavivirus replication in both humans and rhesus macaques through a genome-wide screen.

bioRxiv · May 12, 2022 · PreprintMicrobiology

The Interferon Resistance of Transmitted HIV-1 is a Consequence of Enhanced Replicative Fitness

E. Sugrue, A. Wickenhagen, N. Mollentze, M. A. Aziz, V. B. Sreenu, S. Truxa, L. Tong, A. da Silva Filipe, D. L. Robertson, J. Hughes, S. J. Rihn, S. J. Wilson

The paper identifies that transmitted HIV-1's interferon resistance stems from enhanced replicative fitness rather than specific IFN resistance.

bioRxiv · Dec 18, 2021Microbiology

TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction

R. P. Galao, H. Wilson, K. L. Schierhorn, F. Debeljak, B. S. Bodmer, D. Goldhill, T. Hoenen, S. J. Wilson, C. M. Swanson, S. Neil

This study identifies TRIM25 and ZAP as key factors in type I interferon-mediated inhibition of Ebola virus replication by targeting the viral ribonucleoprotein complex.

bioRxiv · May 23, 2021Microbiology

ADNKA overcomes SARS-CoV2-mediated NK cell inhibition through non-spike antibodies

C. A. Fielding, P. Sabberwal, J. C. Williamson, E. J. Greenwood, E. Crozier, W. Zelek, J. Seow, C. Graham, I. Huettner, J. Edgeworth, B. P. Morgan, K. Ladell, M. Eberl, I. R. Humphreys, B. Merrick, , R. J. Stanton

This study identifies ADNKA as a mechanism by which SARS-CoV-2-infected cells evade NK cell inhibition, showing that non-spike antibodies drive sustained NK activation and cytokine production.

bioRxiv · Apr 6, 2021Immunology

In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2

A. M. Szemiel, A. Merits, R. J. Orton, O. MacLean, A. Wickenhagen, G. Lieber, R. M. Pinto, M. L. Turnbull, S. Wang, D. Mair, A. da Silva Filipe, B. J. Willett, S. J. Wilson, A. H. Patel, E. C. Thomson, , M. E. Stewart

This study shows that in vitro evolution of SARS-CoV-2 under remdesivir selects for resistant mutations, but these mutations do not spread widely in global variants.

bioRxiv · Feb 1, 2021Microbiology

Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.

Y.-T. Lin, S. Chiweshe, D. McCormick, A. Raper, A. Wickenhagen, V. R. DeFilippis, E. Gaunt, P. Simmonds, S. J. Wilson, F. Grey

This study shows HCMV evades ZAP detection by suppressing CpG dinucleotides in its IE1 gene, and TRIM25 regulates ZAP isoform expression.

bioRxiv · Jan 7, 2020Microbiology

TRIM69 inhibits Vesicular Stomatitis Indiana Virus (VSIV)

S. J. Rihn, M. A. Aziz, D. G. Stewart, J. Hughes, M. L. Turnbull, M. Varela, E. Sugrue, C. S. Herd, M. Stanifer, S. P. Sinkins, M. Palmarini, S. J. Wilson

This study identifies TRIM69 as an interferon-induced gene that potently inhibits VSIV, with specific antiviral activity and evolutionary signatures of positive selection.

bioRxiv · Jun 13, 2019Microbiology

Insights into circovirus host range from the genomic fossil record.

T. P. W. Dennis, P. J. Flynn, W. M. De Souza, J. B. Singer, C. Moreau, S. J. Wilson, R. J. Gifford

This study identifies circovirus-related sequences in animal genomes, revealing cyclovirus infection in insects and questioning their role as vertebrate pathogens.

bioRxiv · May 21, 2018Microbiology

The evolution, distribution and diversity of endogenous circoviral elements

T. P. W. Dennis, W. M. Souza, S. Marsile-Medun, J. B. Singer, S. J. Wilson, R. J. Gifford

This study identifies and characterizes endogenous circoviral elements across vertebrate genomes, revealing their evolutionary history and host relationships.

bioRxiv · Jan 16, 2018Evolutionary Biology