Author

Thomas C. Ferrante

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Donald E. IngberiD· 3 shared Adama Marie SesayiD· 2 shared Kostyantyn Shcherbina· 2 shared Susan L. MarqueziD· 2 shared Zohreh IzadifariD· 2 shared Aakanksha GulatiiD· 1 shared Abidemi JunaidiD· 1 shared Amanda R. GravelineiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBioengineering

Donald E. IngberORCID

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Author profile →

5 papers

Recent·Most cited

A platform for automated training of mammalian cell physiology

Patrick Erickson, Douglas Hazel, Ramses Martinez, Kostyantyn Shcherbina, Susan L. Marquez, Thomas C. Ferrante, Katarina Johnson, Angelina Pimkina, Hananel Hazan, Juanita Mathews, Adama Marie Sesay, Michael G. Levin

The paper introduces a platform called the Cell Trainer for automated training of mammalian cells using timed drug pulses and fluorescence imaging, demonstrating sensitization-like dynamics and feedback control in single-cell responses.

bioRxiv · Aug 17, 2026 · PreprintBioengineering

Cytokines control the physical state of immune tissue

Debraj Ghose, Thomas C. Ferrante, Donald E. Ingber

The paper shows cytokines control the physical state of immune tissue by modulating the fluidity of B cell structures, revealing a new biophysical mechanism of immune regulation.

bioRxiv · Oct 28, 2025 · PreprintBiophysics

Induction of cervical dysfunction associated with preterm birth by IL-1 and dysbiotic microbiome revealed in human endocervix chips

Anna Stejskalová, Karina Calderon, David Benson Chou, Aakanksha Gulati, Jéssica F. Feitor, Zohreh Izadifar, Ola Gutzeit, Yasmine Bouchibti, Siyu Chen, Roberto Plebani, Justin Cotton, Jasmine G. Hughes, Thomas C. Ferrante, Bogdan Budnik, Girija Goyal, , Donald E. Ingber

The paper uses human endocervix chips to show that IL-1 receptor antagonists may prevent preterm labor by reducing cervical dysfunction.

bioRxiv · May 1, 2025 · PreprintBioengineering

Organ Chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels

Zohreh Izadifar, Bérénice Charrez, Micaela Almeida, Stijn Robben, Kanoelani T. Pilobello, Janet van der Graaf-Mas, Max Benz, Susan L. Marquez, Thomas C. Ferrante, Kostyantyn Shcherbina, Russell Gould, N. T. LoGrande, Adama Marie Sesay, Donald E. Ingber

This paper introduces Organ Chips with integrated sensors for continuous metabolic monitoring under controlled oxygen levels, demonstrating functionality in human Gut and Liver Chip cultures.

Biosensors and Bioelectronics · Aug 17, 2024Peer-reviewedBioengineering

Fine tuning of CpG spatial distribution with DNA origami for improved therapeutic cancer vaccination

Yang C. Zeng, Olivia J. Young, Christopher M. Wintersinger, Frances M. Anastassacos, James I. MacDonald, Giorgia Isinelli, Maxence O. Dellacherie, Miguel C. Sobral, Haiqing Bai, Amanda R. Graveline, Andyna Vernet, Melinda Sanchez, Kathleen Mulligan, Young–Jin Choi, Thomas C. Ferrante, , William M. Shih

This study developed a DNA origami-based cancer vaccine that co-delivers antigen and CpG immune adjuvant with an optimal nanospacing for Th1 immune polarization.

bioRxiv · Jun 8, 2022 · PreprintSynthetic Biology