Author

Thomas McMahon-Skates

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Pathology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Marc Samuel ShermaniD· 2 shared Wolfram GoesslingiD· 2 shared Adam J. RubiniD· 1 shared Alex K. ShalekiD· 1 shared Alexandra Matschiner· 1 shared Benjamin E. MeadiD· 1 shared Benjamin IzariD· 1 shared Brandon M. LehrichiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSystems Biology

Marc Samuel ShermanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

Constantine N. Tzouanas, Jessica E.S. Shay, Marc Samuel Sherman, Adam J. Rubin, Benjamin E. Mead, Tyler T. Dao, Junyan Tao, Brandon M. Lehrich, George M. Eng, Jeffrey Patterson-Fortin, Titus Butzlaff, Miyeko Mana, Kellie E. Kolb, Chad Michael Walesky, Brian J. Pepe-Mooney, , Alex K. Shalek

The paper shows chronic metabolic stress in liver cells drives developmental programs and functional loss, mirroring tumor states and predicting poor cancer survival.

Cell · Dec 22, 2025Peer-reviewedSystems Biology

A Conserved Landscape of Chemokine Receptor Co-expression Defines the Functional States of CD8+ T Cells in Melanoma

Rodney Macedo, David W Harle, Kevin Hoffer-Hawlik, Ximi Kevin Wang, Thomas McMahon-Skates, Alexandra Matschiner, Kirubel Belay, Yvonne M. Saenger, Benjamin Izar, Elham Azizi, Ran Reshef

The paper identifies co-expression patterns of chemokine receptors on CD8+ T cells that distinguish anti-tumor efficacy from off-target toxicity in melanoma.

bioRxiv · Dec 16, 2025 · PreprintImmunology

Harmonizing terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) with multiplexed iterative immunofluorescence enriches spatial contextualization of cell death

Marc Samuel Sherman, Thomas McMahon-Skates, Lindsey S. Gaston, Sonya W. Katzen, Joseph A. Majzoub, Wolfram Goessling

This paper harmonizes TUNEL with multiplexed immunofluorescence to improve spatial contextualization of cell death in tissues.

Cell Reports Methods · May 1, 2025Peer-reviewedPathology