Author

U. Shrestha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Chaudhary· 1 shared A. Dickson· 1 shared A. Evdokimov· 1 shared A. M. Razavi· 1 shared A. Vinitsky· 1 shared A.-M. Kukuyan· 1 shared B. Mostofian· 1 shared B. Ruprecht· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMicrobiology

A. Chaudhary

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Identification and Characterization of Probiotics Isolates from Indigenous Chicken (Gallus domesticus) of Nepal

M. Gupta, R. Raut, S. Manandhar, A. Chaudhary, U. Shrestha, S. Dangol, S. GC, K. R. Budha, G. Karki, S. D. Sanchez, C. Gortazar, J. de la Fuente, P. G. Rajbhandari, P. Manandhar, R. Napit, D. Karmacharya

The paper isolates and characterizes potential probiotic bacteria from indigenous chickens in Nepal, identifying four Lactobacillus strains with probiotic properties.

bioRxiv · Jul 12, 2022 · PreprintMicrobiology

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T. Dixon, D. MacPherson, B. Mostofian, T. Dauzhenka, S. Lotz, D. McGee, S. Shechter, U. Shrestha, R. Wiewiora, Z. A. McDargh, F. Pei, R. Pal, J. V. Ribeiro, T. Wilkerson, V. Sachdeva, , J. A. Izaguirre

This paper predicts atomic-resolution structures of degrader-mediated ternary complexes using combined HDX-MS and molecular dynamics simulations, validated by experimental data.

bioRxiv · Sep 26, 2021 · PreprintBiophysics

Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Malignant Mesothelioma

E. Sementino, Y. Kadariya, M. Cheung, C. W. Menges, Y. Tan, A.-M. Kukuyan, U. Shrestha, S. Karchugina, K. Q. Cai, S. Peri, J. S. Duncan, J. Chernoff, J. R. Testa

This study shows that inactivating Pak2 reduces tumor development in Nf2-deficient mice, suggesting PAK inhibition could be a therapeutic strategy for NF2-deficient cancers.

bioRxiv · Jun 30, 2020 · PreprintCancer Biology