Author

V. M. Bruno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

A. C. Shetty· 3 shared A. S. Ibrahim· 2 shared C. McCracken· 2 shared A. Alqarihi· 1 shared A. Balfour· 1 shared A. G. Mikos· 1 shared A. M. Tatara· 1 shared A. P. Mitchell· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

A. C. Shetty

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mucoricin is a Ricin-Like Toxin that is Critical for the Pathogenesis of Mucormycosis

S. Soliman, C. Baldin, Y. Gu, S. Singh, T. Gebremariam, M. Swidergall, A. Alqarihi, E. Youssef, S. Alkhazraji, A. Pikoulas, C. Perske, V. Venkataramani, A. Rich, V. M. Bruno, J. C. Dunning Hotopp, , A. S. Ibrahim

This paper identifies mucoricin, a ricin-like toxin produced by Mucorales fungi, critical for mucormycosis pathogenesis and a potential therapeutic target.

bioRxiv · Jan 13, 2021Microbiology

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung

H. Liu, W. Xu, V. M. Bruno, Q. T. Phan, N. V. Solis, C. A. Woolford, R. Ehrlich, A. C. Shetty, C. McCracken, J. Lin, A. P. Mitchell, S. G. Filler

The paper identifies two transcription factors, RlmA and Ace1, critical for Aspergillus fumigatus virulence by analyzing gene expression during lung infection in mice.

bioRxiv · Dec 23, 2020Microbiology

Tobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy

N. Lyons, I. Softley, A. Balfour, C. Williamson, H. O'Brien, A. C. Shetty, V. M. Bruno, S. Diezmann

This paper introduces Manduca sexta caterpillars as a novel invertebrate host model for studying fungal virulence and drug efficacy, showing susceptibility to key yeast pathogens and measurable disease progression.

bioRxiv · Apr 30, 2020Microbiology

Tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds

S. Wurster, A. M. Tatara, N. D. Albert, A. S. Ibrahim, J. Heitman, S. C. Lee, A. C. Shetty, C. McCracken, K. T. Graf, A. G. Mikos, V. M. Bruno, D. P. Kontoyiannis

This study shows that tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds, with potential therapeutic implications for trauma-related mucormycosis.

bioRxiv · Feb 14, 2020Microbiology