Author

E. Youssef

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. Alkhazraji· 3 shared T. Gebremariam· 3 shared Y. Gu· 3 shared A. S. Ibrahim· 2 shared A. A. Seyhan· 1 shared A. Alqarihi· 1 shared A. Ibrahim· 1 shared A. Mueller· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

S. Alkhazraji

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Efficacy of an oral lipid nanocrystal (LNC) formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis

Y. Gu, T. Gebremariam, S. Alkhazraji, E. Youssef, S. El-Gamal, T. Matkovits, J. Cobb, R. Mannino, A. Ibrahim

This study compares the efficacy of oral MAT2203 to intravenous LAMB in a neutropenic mouse model of mucormycosis, finding MAT2203 as effective in survival and fungal burden reduction.

bioRxiv · Nov 22, 2023Microbiology

Mucoricin is a Ricin-Like Toxin that is Critical for the Pathogenesis of Mucormycosis

S. Soliman, C. Baldin, Y. Gu, S. Singh, T. Gebremariam, M. Swidergall, A. Alqarihi, E. Youssef, S. Alkhazraji, A. Pikoulas, C. Perske, V. Venkataramani, A. Rich, V. M. Bruno, J. C. Dunning Hotopp, , A. S. Ibrahim

This paper identifies mucoricin, a ricin-like toxin produced by Mucorales fungi, critical for mucormycosis pathogenesis and a potential therapeutic target.

bioRxiv · Jan 13, 2021Microbiology

Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells

L. Zhou, K. Huntington, S. Zhang, L. Carlsen, E.-Y. So, C. Parker, I. Sahin, H. Safran, S. Kamle, C.-M. Lee, C.-G. Lee, J. A. Elias, K. S. Campbell, M. T. Naik, W. J. Atwood, , W. El-Deiry

This study shows MEK inhibitors reduce ACE2 and inflammatory cytokines, enhance NK cell activity, and block SARS-CoV-2 pseudovirus infection in human cells.

bioRxiv · Aug 2, 2020 · PreprintCell Biology

Preserving Vascular Integrity Protects Mice Against Multidrug-Resistant Gram-Negative Bacterial Infection

T. Gebremariam, L. Zhang, S. Alkhazraji, Y. Gu, E. Youssef, Z. Tong, E. Kish-Trier, C. V. Araujo, B. Rich, S. W. French, D. Li, A. Mueller, S. Odelberg, W. Zhu, A. S. Ibrahim

This study shows that inhibiting ARF6 protects mice from MDR Gram-negative bacterial infections by preserving vascular integrity.

bioRxiv · Feb 18, 2020Microbiology