Author

V. Mastrodomenico

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

B. C. Mounce· 2 shared A. Jaochimiak· 1 shared A. V. Ivanov· 1 shared B. C. Dickinson· 1 shared B. F. Kafsack· 1 shared B. L. Fung· 1 shared B. Mounce· 1 shared B. Schuster· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

B. C. Mounce

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3 papers

Recent·Most cited

A non-canonical sensing pathway mediates Plasmodium adaptation to AA deficiency

I. M. Marreiros, S. Marques, V. Mastrodomenico, B. Mounce, C. T. Harris, B. F. Kafsack, O. Billker, V. Zuzarte-Luis, M. M. Mota

This study identifies a non-canonical AA-sensing pathway in Plasmodium that enables adaptation to amino acid deficiency through kinases eIK1 and eIK2.

bioRxiv · Dec 1, 2022 · PreprintMicrobiology

Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro

N. Drayman, K. A. Jones, S.-A. Azizi, H. M. Froggatt, K. Tan, N. Ivanova Maltseva, S. Chen, V. Nicolaescu, S. Dvorkin, K. Furlong, R. S. Kathayat, M. R. Firpo, V. Mastrodomenico, E. A. Bruce, M. M. Schmidt, , S. Tay

The paper screens 1,900 drugs to find inhibitors of SARS-CoV-2 replication, identifies masitinib as a 3CLpro inhibitor effective in vitro, and shows its broad anti-viral activity.

bioRxiv · Aug 31, 2020Microbiology

Virion-associated spermidine transmits with Rift Valley fever virus particles to maintain infectivity

V. Mastrodomenico, J. J. Esin, S. Qazi, O. S. Omoba, B. L. Fung, M. A. Khomutov, A. V. Ivanov, S. Mukhopadhyay, B. C. Mounce

This study identifies spermidine as a critical polyamine associated with Rift Valley fever virus particles that maintains infectivity, highlighting a new antiviral target.

bioRxiv · Jan 23, 2020 · PreprintMicrobiology