K. A. Jones

Cooperative regulation of C1-domain membrane recruitment polarizes atypical Protein Kinase C

This study identifies the C1 domain of aPKC as a phospholipid interaction module that targets aPKC to the membrane of Drosophila neural stem cells, with other domains restricting its activity to the apical membrane during mitosis.

Urinary glucocorticoids in harbour seal (Phoca vitulina) pups during rehabilitation

This study measures urinary glucocorticoids in harbour seal pups during rehabilitation, finding that prednisone levels correlate with pup mass and suggest physiological stressors.

Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

This study shows that cannabidiol inhibits SARS-CoV-2 replication and enhances the host innate immune response in lung cells and human patients.

Chemical ecology of an apex predator life cycle

The paper examines how microbial symbiosis influences chemical ecology during an insect's life cycle by analyzing trophic interactions, metabolomics, and gene regulation in nematodes and bacteria.

Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro

The paper screens 1,900 drugs to find inhibitors of SARS-CoV-2 replication, identifies masitinib as a 3CLpro inhibitor effective in vitro, and shows its broad anti-viral activity.

Interpretable multimodal deep learning for real-time pan-tissue pan-disease pathology search on social media

The paper develops interpretable deep learning models to search for similar disease states across social media and PubMed using histopathology images and clinical data, achieving high precision in real-time diagnosis assistance.

Rapid multicomponent bioluminescence imaging via substrate unmixing

This paper introduces a method for rapid, multiplexed bioluminescence imaging using substrate unmixing to detect multiple luciferases in vitro and in vivo.