Author

W. K. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. Park· 2 shared J.-L. Lee· 2 shared K. H. Nam· 2 shared K. Lee· 2 shared S. Baek· 2 shared S. Park· 2 shared Y. Cho· 2 shared Y. Shen· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

J. Park

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Author profile →

5 papers

Recent·Most cited

Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme

C.-G. Wu, V. K. Balakrishnan, P. S. Parihar, K. Konovolov, Y.-C. Chen, R. A. Merrill, H. Wei, B. Carragher, R. Sundaresan, Q. Cui, B. E. Wadzinski, M. R. Swingle, A. Musiyenko, R. Honkanen, W. K. Chung, , Y. Xing

The paper investigates the structural and functional dynamics of the PP2A-B56δ holoenzyme, showing how mutations linked to intellectual disability affect its allosteric network and phosphorylation rates.

bioRxiv · Mar 9, 2023 · PreprintBiochemistry

Context-dependent functions of mitochondria protein quality control in lung

L. Xu, C. Tan, J. Barr, N. Talaba, J. Verheyden, J. S. Chin, S. Gaboyan, I. Advani, R. M. Elgamal, K. J. Gaulton, G. Lin, K. Afshar, E. Golts, A. Meier, L. C. Alexander, , X. Sun

This study shows that mitochondrial protein quality control via LONP1 is context-dependent in lung epithelial cells, affecting proliferation, differentiation, and migration through the integrated stress response.

bioRxiv · Dec 8, 2022 · PreprintCell Biology

Combination of an inject-and-transfer system for serial femtosecond crystallography

K. Lee, J. Kim, S. Baek, J. Park, S. Park, J.-L. Lee, W. K. Chung, Y. Cho, K. H. Nam

This paper introduces a new sample delivery method for serial femtosecond crystallography, enabling reliable crystal deposition and successful structure determination of lysozyme.

bioRxiv · Feb 8, 2022Biophysics

Human stem cell model of HNF1A deficiency shows uncoupled insulin to C-peptide secretion with accumulation of abnormal insulin granules

B. J. Gonzalez, H. Zhao, J. Niu, D. J. Williams, J. Lee, C. N. Goulbourne, Y. Xing, Y. Wang, J. Oberholzer, X. Chen, C. A. LeDuc, W. K. Chung, H. M. Colecraft, J. Gromada, Y. Shen, , D. Egli

This study uses human stem cells to show that HNF1A deficiency leads to impaired insulin secretion, altered insulin:C-peptide ratios, and abnormal secretory granules in beta-cells.

bioRxiv · Jan 26, 2021Cell Biology

Viscous medium-based crystal support in sample holder for fixed-target serial femtosecond crystallography

K. Lee, D. Lee, S. Baek, J. Park, S. J. Lee, S. Park, W. K. Chung, J.-L. Lee, H.-S. Cho, Y. Cho, K. H. Nam

This paper introduces a viscous medium-based sample holder for fixed-target serial femtosecond crystallography, enabling stable crystal support for various sizes and shapes.

bioRxiv · Dec 31, 2019Biophysics