Author

Wenjia Qu

Garvan Institute of Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amanda KhouryiD· 2 shared Catherine Elizabeth CaldoniD· 2 shared Clare StirzakeriD· 2 shared Jenny Z. Song· 2 shared Qian DuiD· 2 shared Shalima S. Nair· 2 shared Susan J. ClarkiD· 2 shared Aliza Yong· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Amanda KhouryORCID

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2 papers

Recent·Most cited

Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer

Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman, Elyssa M. Campbell, Kee-Ming Chia, Qian Du, Geraldine Laven‐Law, Shalima S. Nair, Aliza Yong, Ashleigh Wilkinson, Samuel Clifton, Heloisa Helena Milioli, Sarah Alexandrou, Catherine Elizabeth Caldon, Jenny Z. Song, , Susan J. Clark

This study shows that Decitabine suppresses tumour growth in ER+ breast cancer by inducing DNA hypomethylation and altering 3D chromatin structure.

Nature Structural & Molecular Biology · Jan 5, 2024Peer-reviewedMolecular Biology

Replication timing shapes the cancer epigenome and the nature of chromosomal rearrangements

Qian Du, Saul A. Bert, Nicola J. Armstrong, Catherine Elizabeth Caldon, Jenny Z. Song, Shalima S. Nair, Cathryn M. Gould, Phuc‐Loi Luu, Amanda Khoury, Wenjia Qu, Elena Zotenko, Clare Stirzaker, Susan J. Clark

This study shows that replication timing influences epigenetic changes and chromosomal rearrangements in cancer by linking early and late replication to specific methylation and histone modifications.

bioRxiv · Jan 22, 2018 · PreprintGenomics