Y. Tang

This study reviews scientific research on farmers' roles in agricultural adaptation to climate change from 2008-2017, finding limited global representation and methodological diversity.

This paper develops an anti-MUC1 antibody-drug conjugate targeting a GSTA glycosite-signature epitope, showing potent antitumoral efficacy and low toxicity in NSCLC models.

This study uses machine learning to predict TCM Meridians based on molecular features of herb compounds, achieving 83% accuracy.

This study identifies sex pheromone plasmids as a mechanism for disseminating linezolid-resistance in E. faecalis through plasmid transfer.

This study identifies ISLR as a stromal factor that suppresses epithelial Hippo signaling to promote intestinal regeneration and cancer.

This study characterizes the NF-κB protein in the sponge Amphimedon queenslandica, showing conserved features with vertebrates but distinct regulatory mechanisms.

This study shows lung cancer exosomes promote MDSC expansion via miR-21a/PDCD4/IL-6/STAT3 pathway, enhancing tumor growth.

The paper develops a biosensor platform called SPAR for rapid and sensitive pathogen detection using engineered cells and antibodies.

The paper identifies 202 differentially expressed genes in EBV-induced lymphomas using a mouse model and highlights key genes involved in the oncogenic process.

This study shows that LSD1, recruited by Blimp-1, represses PD-1 expression during acute infection by removing activating histone marks and is necessary for remethylation of the Pdcd1 locus.

This study conducts a histone acetylome-wide association study (HAWAS) of tuberculosis, identifying differentially acetylated loci and their association with immune phenotypes.

The paper identifies an NRPS-like enzyme in fungi that catalyzes the reductive conversion of glycine betaine to choline, revealing its role in choline biosynthesis and homeostasis.

This paper develops a method to directly synthesize EM-visible gold nanoparticles on genetically encoded tags for single-molecule visualization in cells, achieving high labeling efficiency in both prokaryotic and eukaryotic cells.

This paper determines the structural basis for the stereoselective dehydration and hydrogen-bonding catalysis by LepI, revealing how it functions as a multifunctional pericyclase.

This study shows that delivering a RyR2-targeting nanobody via AAV9 improves cardiac function in rat models of ischemic heart failure by reducing calcium leak and reversing dysfunction.

This study shows that B1a cells reduce liver inflammation and fibrosis in Schistosoma japonicum infection by secreting IL-10, which suppresses monocyte infiltration and inflammatory cytokines.

The paper identifies essential genes for apicoplast biogenesis in P. falciparum through a mutagenesis screen, revealing new proteins and functions with potential drug targets.

This study shows TP, activated by Twist1, promotes HCC metastasis and VM via pentose Warburg effect by linking pentose phosphate pathway and glycolysis.

This study investigates how peiminine induces apoptosis in HepG2 cells through both extrinsic and intrinsic pathways, showing dose- and time-dependent effects.

The paper shows that gliding bacteria, specifically Capnocytophaga gingivalis, transport non-motile bacteria as cargo, shaping the spatial organization of polymicrobial communities.