Author

Y.-Y. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:plant (other)· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

Y. Li· 3 shared F. Huang· 2 shared G.-B. Li· 2 shared H. Wang· 2 shared H.-B. Luo· 2 shared J. Fan· 2 shared J. Liu· 2 shared J.-H. Zhao· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPlant Biology

Y. Li

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ancient DNA Reveals China as a Historical Genetic Melting Pot in Tiger Evolution

X. Sun, Y.-C. Liu, M. P. Tiunov, D. O. Gimranov, Y. Zhuang, Y. Han, C. A. Driscoll, Y.-H. Pang, C. Li, Y. Pan, M. S. Velasco, S. Gopalakrishnan, R.-Z. Yang, B.-G. Li, K. Jin, , S.-J. Luo

This study uses ancient DNA to trace tiger evolution, revealing China as a genetic melting pot and resolving taxonomic disputes among tiger subspecies.

bioRxiv · Sep 14, 2022 · PreprintEvolutionary Biology

An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures.

J. Shumeng, F. Alisafaei, H. Yuan, X. Peng, Y.-Y. Huang, J. H. Miner, G. M. Genin, H. Y. Suleiman

The paper develops an ex vivo culture model of kidney podocytes to study injury recovery, revealing mechanosensitive sarcomere-like structures that template synaptopodin.

bioRxiv · Nov 3, 2021Cell Biology

Proteasome maturation factor UMP1 confers broad-spectrum disease resistance by modulating H2O2 accumulation in rice

X.-H. Hu, J. Fan, J.-L. Wu, S. Shen, J.-X. He, J. Liu, H. Wang, Y. Zhu, G.-B. Li, J.-H. Zhao, J. Xu, D.-Q. Li, M. Pu, Z.-X. Zhao, S.-X. Zhou, , W.-M. Wang

A natural allele of rice UMP1 promotes resistance to multiple pathogens by boosting H2O2 accumulation.

bioRxiv · Mar 3, 2021 · PreprintPlant Biology

Insights into the susceptibility of rice to a floral disease

G.-B. Li, J. Fan, J. Liu, J.-L. Wu, X.-H. Hu, J.-X. He, S. Shen, H. Wang, Y. Zhu, F. He, H. Gao, Z. G. N. Gishkori, J.-H. Zhao, Y. Li, F. Huang, , W.-M. Wang

The fungal pathogen Ustilaginoidea virens disarms chitin-triggered immunity in rice flower via a secreted chitinase, revealing a mechanism of disease susceptibility.

bioRxiv · Mar 3, 2021 · PreprintPlant Biology

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Z. Li, X. Li, Y.-Y. Huang, Y. Wu, L. Zhou, R. Liu, D. Wu, L. Zhang, H. Liu, X. Xu, Y. Zhang, J. Cui, C.-G. Zhan, X. Wang, H.-B. Luo

This paper identifies potent SARS-CoV-2 main protease inhibitors using accelerated free energy perturbation-based virtual screening of existing drugs, finding 15 inhibitors from 25 predicted drugs.

Proceedings of the National Academy of Sciences · Oct 13, 2020Peer-reviewedBiophysics

Enantiomers of Chloroquine and Hydroxychloroquine Exhibit Different Activities Against SARS-CoV-2 in vitro, Evidencing S-Hydroxychloroquine as a Potentially Superior Drug for COVID-19

G. Li, J. Sun, Y.-Y. Huang, Y. Li, Y. Shi, Z. Li, X. Li, F. H. Yang, J. Zhao, H.-B. LUO, T. Y. Zhang, X. Zhang

This study shows that S-enantiomers of chloroquine and hydroxychloroquine are more effective against SARS-CoV-2 and less toxic than their R-enantiomers, suggesting S-HCQ as a better treatment option for COVID-19.

bioRxiv · May 26, 2020 · PreprintBiochemistry