Author

Yangqi Su

University of Maryland, Baltimore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jonathan Shea· 2 shared Wei LiiD· 2 shared Zhengchang SuiD· 2 shared Aagam S. ShahiD· 1 shared Alfredo MolinoloiD· 1 shared Alon Katz· 1 shared Aniruddha J. DeshpandeiD· 1 shared Artem R CherkasoviD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersDevelopmental Biology

Jonathan Shea

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

pertTF: context-aware AI modeling for genome-scale and cross-system perturbation prediction

Yangqi Su, Dingyu Liu, Vipin K. Menon, Bicna Song, Samuel Boccara, Nan Zhang, Huan Zhao, Jiahui Hazel Zhao, Lei Wang, Nan Hu, Mpathi Nzima, Alon Katz, Bharath Kumar Swargam, Seth A. Ament, Yarui Diao, , Wei Li

The paper introduces pertTF, a transformer-based model for predicting genetic perturbation responses, showing improved performance in expression prediction and cell identity shifts across cellular contexts.

bioRxiv · Mar 16, 2026 · PreprintBioinformatics

Targeting the translation initiation complex in therapy-resistant and metastatic melanoma

Yongmei Feng, Ximena Diaz-Olea, Xiurong Ke, Mariia Radaeva, Mehdi Amiri, Hyunjeong Joo, Maryam Jafari, Hyungsoo Kim, Aniruddha J. Deshpande, Steven H. Olson, Predrag Jovanović, Yangqi Su, Aagam S. Shah, Ian Pass, Qiyun Deng, , Ze’ev A. Ronai

This study identifies M19-6 as a small molecule that disrupts the eIF4F complex, reducing melanoma growth and metastasis while sparing melanocytes.

bioRxiv · Nov 20, 2024 · PreprintCancer Biology

Single-cell RNA-seq Reveals Early Transcriptional Programs of the Maternal to Zygote Transition in Mice and Rats

Yangqi Su, Jane Kouranova, Jonathan Shea, Xiaoxia Cui, Zhengchang Su

This study uses single-cell RNA-seq to analyze transcriptomic changes during the maternal to zygote transition in mice and rats, revealing similar but distinct transcriptional programs in both species.

bioRxiv · Sep 30, 2024 · PreprintDevelopmental Biology

Transcriptomic Analysis of the Spatiotemporal Axis of Oogenesis and Fertilization in C. elegans

Yangqi Su, Jonathan Shea, Darla DeStephanis, Zhengchang Su

This study performs single-cell RNA-seq on C. elegans germline sections to analyze gene expression and splicing during oogenesis and fertilization, revealing novel insights into germline-somatic interactions.

Frontiers in Cell and Developmental Biology · Aug 19, 2024Peer-reviewedDevelopmental Biology