Author

Zhe Li

Chinese Institute for Brain Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Genomics· 1 Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:electrophysiology· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1

Frequent Co-Authors

Alex KangiD· 1 shared Andrew J. BorstiD· 1 shared Asim K. BeraiD· 1 shared Banumathi SankaraniD· 1 shared Bo LiuiD· 1 shared Byeongdu LeeiD· 1 shared Chenguang Wu· 1 shared Danny D. SahtoeiD· 1 shared

Activity by Year

2017-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperSynthetic Biology

Alex KangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Programmable De Novo Design of Mesoporous Protein Crystal Frameworks

Zhe Li, Shunzhi Wang, William Sheffler, Yang Hsia, Byeongdu Lee, Greg L. Hura, Muammer Y. Yaman, Bo Liu, Ryan D. Kibler, Neville P. Bethel, David Chmielewski, Danny D. Sahtoe, Wei Yang, Hao Shen, Hanlun Jiang, , David A. Baker

This paper presents a modular strategy to design programmable, highly porous protein crystals with tunable architectures and composition, enabling applications in catalysis and biomedicine.

bioRxiv · Aug 26, 2026 · PreprintSynthetic Biology

Economic and Social Modulations of Innate Decision-Making in Mice Exposed to Visual Threats

Zhe Li, Jiahui Wang, Yidan Sun, Jialin Li, Ling-yun Li, Ya-tang Li

This study investigates how threat intensity, reward value, and social hierarchy influence decision-making in mice exposed to visual threats using a behavioral paradigm and computational modeling.

eLife · Aug 18, 2026Peer-reviewedNeuroscience

A Minimally Invasiveness Hybrid Brain-Computer Interface: A Distributed, Scalable and Evolvable Architecture for Whole Brain Access

Zhe Li, Na Liu, Li Wan, Mengting Liu, Chenguang Wu

This paper introduces a minimally invasive hybrid brain-computer interface that improves signal quality and scalability over existing non-invasive and invasive systems.

bioRxiv · Jul 15, 2026 · PreprintBioengineering

5-Formylcytosine controls nucleosome positioning through covalent histone-DNA interaction

Eun‐Ang Raiber, Guillem Portella, Sergio Martínez Cuesta, Robyn E. Hardisty, Pierre Murat, Zhe Li, Mario Iurlaro, Wendy Dean, Julia Spindel, Dario Beraldi, Mark A. Dawson, Wolf Reik, Shankar Balasubramanian

This study shows that 5-formylcytosine (5fC) influences nucleosome positioning through covalent histone-DNA interactions in mouse embryonic stem cells.

bioRxiv · Nov 24, 2017 · PreprintGenomics