Margot Zahm

Microglial Foxo3 shapes dopaminergic vulnerability in Parkinson disease

This study identifies Foxo3 as a key regulator of dopaminergic vulnerability through microglial mechanisms, showing that baseline microglial state, rather than acute transcriptional responses, determines neurodegeneration in Parkinson's disease.

Multi-genome comparisons reveal gain-and-loss evolution of the anti-Mullerian hormone receptor type 2 gene, an old master sex determining gene, in Percidae

The paper compares genomes across multiple fish species to study the evolutionary changes in the amhr2bY gene, a key sex-determining gene, revealing gains and losses in different Percidae species.

An ancient truncated duplication of the anti-Mullerian hormone receptor type 2 gene is a potential conserved master sex determinant in the Pangasiidae catfish family

The paper identifies a truncated duplication of the amhr2 gene on the Y chromosome in Pangasiid catfishes as a conserved master sex-determining gene.

Sex chromosome and sex locus characterization in the goldfish, Carassius auratus

This study characterizes the sex determination system and sex chromosomes in goldfish, identifying a large non-recombining region on linkage group 22 as the likely Y chromosome and developing sex-linked genetic markers.

Genome sequence of the euryhaline Javafish medaka, Oryzias javanicus: a small aquarium fish model for studies on adaptation to salinity.

The paper presents a high-quality draft genome assembly of Oryzias javanicus, focusing on its adaptation to salinity.

Characterization of a Y-specific duplication/insertion of the anti-Mullerian hormone type II receptor gene based on a chromosome-scale genome assembly of yellow perch, Perca flavescens

The paper presents a chromosome-scale genome assembly of yellow perch and identifies a Y-specific duplication of the amhr2 gene as a candidate sex determination gene.