Author
Manchester Academic Health Science CentreORCID 0000-0002-4045-0933Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Sébastien Brûlé, Maelenn Chevreuil, Osvaldo Burastero…·Bertrand D. E. Raynal
This study benchmarks DSF across labs, showing variability in thermal stability parameters due to instruments, workflows, and fluorescence readouts, with harmonization and centralized analysis improving consistency.
Holly L. Birchenough, Jonathan F. Popplewell, H. Davies-Strickleton…·Thomas A. Jowitt
The paper introduces a high-throughput SPR array to profile GAG-protein interactions, validating it with known proteins and identifying new interactions.
Riley R. Weaver, Anna L. Gray, Saudina Mateus-Gomes…·Douglas P. Dyer
This study shows CXCL4 enters the brain via GAG-binding to BBB proteoglycans and promotes neurogenesis through GAG-mediated oligomerization.
Anokhi Shah, Xiaoli Zhang, M. Snee…·Anthony J. Day
This paper investigates how PTX3's quaternary structure enables HA crosslinking via interactions with HC1, revealing pH-dependent binding and structural flexibility.