Shuxin Li

This study shows that PTEN inhibition improves forelimb motor recovery and circuit remodeling in chronic cervical SCI by enhancing spinal interneuron network recruitment and synaptic input.

The paper maps pre-phrenic interneuron (PP-IN) connectivity to phrenic motor neurons in uninjured and injured spinal cord, revealing intrasegmental and propriospinal pathways and their plasticity after injury.

This study identifies a pathway involving Rtca, Rab10, and Itgb1 that regulates Piezo localization and function, promoting axon regeneration inhibition in Drosophila and mice.

This study shows that deleting PTEN enhances BRAF-driven regeneration of injured sensory axons across the DREZ, enabling long-distance growth into the spinal cord.

This study shows that PTEN inhibition promotes partial diaphragm function recovery and axon growth in chronic cervical spinal cord injury, while PTPσ inhibition does not.

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

This study identifies Lin28a and Lin28b as key regulators of axon regeneration in mammals, showing their ability to promote optic nerve regeneration through miRNA regulation and interaction with PTEN.