Philip G. Haydon

This study identifies astrocytes and D-serine/NMDAR signaling as key mediators of the cognitive benefits of α7nAChRs and their targeting therapeutics in mice.

This study shows that astrocytic lactate supply via MCT4 and MCT2 is essential for maintaining wakefulness and sleep stability by supporting orexinergic neuron activity.

The paper shows that adenosine deficiency in a mouse model of Alzheimer's disease leads to synaptic hyperexcitability during the asymptomatic phase, which can be restored by pharmacologic or dietary interventions.

Genetically encoded voltage imaging reveals presynaptic neuronal activity drives focal astrocyte depolarization, inhibiting glutamate uptake during neuronal activity.