Yichun Shuai

RubyACRs Enable Red-Shifted Optogenetic Inhibition in Freely Behaving Drosophila

This study evaluates RubyACRs as red-shifted optogenetic inhibitors in Drosophila, showing they effectively hyperpolarize neurons and induce circuit-specific behavioral changes.

Driver lines for studying associative learning in Drosophila

The paper introduces a new collection of over 800 split-GAL4 and split-LexA drivers for studying associative learning in Drosophila, covering 300 cell types and enabling functional analysis of neural circuits.

Neural circuit mechanisms for transforming learned olfactory valences into wind-oriented movement

The paper identifies a neuronal circuit in Drosophila that transforms learned olfactory valences into wind-oriented movement by integrating inputs from memory compartments.

A modular chemigenetic calcium indicator enables in vivo functional imaging with near-infrared light

The paper introduces WHaloCaMP, a near-infrared calcium indicator, and demonstrates its use in imaging calcium responses in various organisms.

Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator

The paper identifies a mutation that enhances the sensitivity of a fluorescent voltage indicator, improving its ability to detect both spiking and subthreshold voltage signals in multiple organisms.

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging

The paper introduces a new genetically encoded voltage indicator, Voltron, which improves brightness and photostability for extended in vivo voltage imaging in mice, zebrafish, and fruit flies.