Charles M. Schroeder

This study investigates how ionizable lipids alter endosomal membrane properties to enhance endosomal escape, showing they reduce membrane rigidity and curvature.

This study examines how stereochemistry affects electron transport in peptides through experiments and simulations, showing that stereochemical modifications alter conductance via aromatic interactions or secondary structure effects.

This study uses smFRET to show that opioid ligands modulate Gi protein conformational dynamics, with higher-efficacy agonists promoting open, low-nucleotide-affinity states.

This study investigates how secondary structure influences electron transport in peptides using a combination of experiments and computational methods, revealing a two-state conductance behavior linked to conformational flexibility.

This paper introduces a 2D DNA-based data storage system that encodes information in both sequence and backbone structure, using machine learning for error correction and data reconstruction.

This paper introduces an extended 11-letter DNA alphabet for data storage, using nanopore readout and neural networks to improve accuracy and density.

This paper proposes a method to store quantized images in DNA using signal processing and machine learning to reduce errors and costs without redundant oligos or rewriting.

The paper shows how delta oscillations in primate auditory cortex are reset and entrained by auditory stimuli, using experimental data and a computational model.