Andreu Matamoros‐Angles

Extracellular vesicles released from cortical neurons influence spontaneous activity of recipient neurons.

This study shows that extracellular vesicles from cortical neurons alter spontaneous activity in recipient neurons by increasing postsynaptic potential amplitude.

Deep-Tissue Two-Photon Brain Imaging Enabled by a Tunable Fiber-Optic Dispersive Wave Generator

This paper introduces a tunable fiber-optic dispersive wave generator for deep-tissue two-photon imaging in mouse brains, achieving high-resolution imaging at depths over 450 micrometers.

Multiplexed Brain and Visceral Two-Photon Imaging Using a Simulation-Guided Ultrafast Three-Color Fiber Laser

This paper introduces a three-color ultrafast fiber laser platform for multiplexed two-photon imaging, validated in mouse tissue to visualize multiple cellular structures.

Efficient enzyme-free isolation of brain-derived extracellular vesicles

This paper demonstrates that non-enzymatic methods can isolate brain-derived extracellular vesicles without compromising protein integrity, achieving high yield and purity.

Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases

This study identifies ADAM10-mediated shedding of human PrP at Y226 and shows sPrP associates with misfolded protein aggregates in neurodegenerative diseases.

Behavioral deficits, learning impairment, and enhanced hippocampal excitability in co-isogenic PrnpZH3/ZH3 mice

This study investigates the role of PrPC in hippocampal function using PrnpZH3/ZH3 mice, finding behavioral deficits, learning impairment, and increased excitability without enhanced LTP.

PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure

The paper identifies PP4-dependent HDAC3 dephosphorylation as a mechanism distinguishing axonal regeneration from regenerative failure in nerve injuries.