Author

Marcel S. Woo

University Medical Center Hamburg-EppendorfORCID 0000-0002-1306-2708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Katarzyna M. GrochowskaiD· 3 shared Manuel Alexander FrieseiD· 2 shared Alexandros HadjilaouiD· 1 shared Anja Maria OelschlegeliD· 1 shared Anna KarpovaiD· 1 shared Annika Schlößer· 1 shared Antonia BeiersdorferiD· 1 shared Berta PuigiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersNeuroscience

Katarzyna M. GrochowskaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Amyloid-β 42-carrying extracellular vesicles are associated with neurodegeneration and neuroinflammation in Alzheimer's disease

Lukas Raich, Mirko Könken, Katarzyna M. Grochowska, Berta Puig, Christina Mayer, Alexandros Hadjilaou, Eckhard Schlemm, Mohsin Shafiq, Götz Thomalla, Tim Ullrich Magnus, Jürgen Gallinat, Tharick Ali Pascoal, Serge G. Gauthier, Markus Glatzel, Min Shi, , Marcel S. Woo

This study identifies Aβ42-carrying extracellular vesicles in plasma as biomarkers associated with neurodegeneration and neuroinflammation in Alzheimer's disease.

bioRxiv · Nov 27, 2025 · PreprintNeuroscience

Astrocytic uptake of posttranslationally modified amyloid-β leads to endolysosomal system disruption and induction of pro-inflammatory signaling

Sarah Wirth, Annika Schlößer, Antonia Beiersdorfer, Michaela Schweizer, Marcel S. Woo, Manuel Alexander Friese, Christian Lohr, Katarzyna M. Grochowska

This study shows that astrocytic uptake of modified Aβ3(pE)-42 disrupts the endolysosomal system, leading to inflammation and synapse loss in Alzheimer's disease.

Glia · Apr 17, 2024Peer-reviewedNeuroscience

Preventing Jacob-induced transcriptional inactivation of CREB protects synapses from β-amyloid in Alzheimer's Disease

Katarzyna M. Grochowska, Guilherme M. Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja Maria Oelschlegel, PingAn Yuanxiang, Irene Reyes‐Resina, Gonca Bayraktar, Sebastian Samer, Christina Spilker, Marcel S. Woo, Markus Morawski, Jürgen Goldschmidt, , Michael R. Kreutz

The paper shows that Nitarsone prevents Aβ-induced CREB inactivation and synaptic loss in AD models by blocking Jacob-mediated signalosome assembly.

The EMBO Journal · Jan 3, 2023Peer-reviewedNeuroscience