Author

Wilhelm Vaysse-Zinkhöfer

Centre National de la Recherche ScientifiqueORCID 0000-0001-6734-1676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

David Paul ToczyskiiD· 1 shared David Viterbo· 1 shared Enya Marie Catherine AlcindoriD· 1 shared Guy‐Franck RichardiD· 1 shared Lucie PoggiiD· 1 shared Nicholas GaraffoiD· 1 shared Stéphane Descorps‐DeclèreiD· 1 shared Valentine MosbachiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

David Paul ToczyskiORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 14, 2025

Cul5Wsb2 uses BCL2 proteins as co-receptors to target Bim for degradation.

Wilhelm Vaysse-Zinkhöfer, Enya Marie Catherine Alcindor, Nicholas Garaffo, David Paul Toczyski

The paper identifies BCL2 proteins as co-receptors for CUL5WSB2 to target BIM for degradation, revealing a novel mechanism in apoptosis regulation with therapeutic implications for neuroblastomas and cancers.

DOI 10.1101/2025.08.14.670414

humanproteomics

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GeneticsPLoS GeneticsPeer-reviewedJul 16, 2020

Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal rearrangements

Valentine Mosbach, David Viterbo, Stéphane Descorps‐Declère…·Guy‐Franck Richard

This study shows that using Cas9 to induce a double-strand break at CTG trinucleotide repeats leads to chromosomal rearrangements, highlighting risks of using Cas9 near microsatellites.

20 citations

yeastCRISPR screen

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