Ian J. Gonzalez

iG6PSnFR: A genetically encoded fluorescent sensor for observing glucose-6-phosphate dynamics in living preparations

The paper develops and validates a genetically encoded fluorescent sensor, iG6PSnFR, for measuring glucose-6-phosphate dynamics across multiple biological contexts.

Spatial Partitioning of Glucose Metabolism Supports Tissue-Specific Metabolic Programs In Vivo

The paper investigates tissue-specific metabolic functions of GPI-1 in C. elegans, showing isoform-specific localization and metabolic roles in different tissues.

Glycogen metabolism acts in neurons to support glycolytic plasticity

This study identifies PYGL-1 as essential for glycolytic plasticity in neurons, revealing two mechanisms that support synaptic function under metabolic stress.

Local and dynamic regulation of neuronal glycolysis in vivo

The paper uses a biosensor to image glycolysis in individual neurons of C. elegans, revealing diverse and adaptable glycolytic states across cell types and conditions.

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

This study identifies ATG-9 trafficking as a mechanism linking presynaptic autophagy to the synaptic vesicle cycle in C. elegans.