Author

Tyler Cannon

Aligning Science Across Parkinson'sORCID 0000-0001-6809-5470Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Heidi May McBrideiD· 2 shared Michel DesjardinsiD· 2 shared Samantha GruenheidiD· 2 shared Ahmed M. FahmyiD· 1 shared Alex TchungiD· 1 shared Ali AhmadiiD· 1 shared Amandine EveniD· 1 shared Benoit BarretteiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Heidi May McBrideORCID

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2 papers

Recent·Most cited

STING dampens the unfolded protein response to enable the presentation of self-antigens on MHC-I during inflammation.

Ahmed M. Fahmy, Ali Ahmadi, Joël Lanoix, Tyler Cannon, Moustafa Nouh Elemeery, Camberly Hernandez, Benoit Barrette, Éric Bonneil, Yong Zhong Xu, Maha Ibrahim, Guillermo Arango Duque, Eric Olivier Audemard, Sébastien Lemieux, Éric Chevet, Erwin Schurr, , Michel Desjardins

The paper shows STING dampens the unfolded protein response to allow self-antigen presentation on MHC-I during inflammation, linking it to immune regulation in Parkinson's disease.

Cell Reports · Jun 1, 2026Peer-reviewedImmunology

A single Citrobacter rodentium infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss

Sriparna Mukherjee, Vladimir Grouza, Alex Tchung, Amandine Even, Moein Yaqubi, Marius Tuznik, Tyler Cannon, Sherilyn Junelle Recinto, Christina Gavino, Marie-Josée Bourque, Nicolas Giguère, Heidi May McBride, Michel Desjardins, Samantha Gruenheid, Jo Anne Stratton, , Louis‐Éric Trudeau

This study shows that a single Citrobacter rodentium infection increases blood-brain barrier permeability and triggers neuroinflammation in Pink1 knockout mice without dopamine neuron loss.

bioRxiv · Dec 24, 2024 · PreprintNeuroscience